ASYMMETRIC REDUCTION OF ALPHA-KETO ACETALS WITH POTASSIUM 9-O-(1,2-ISOPROPYLIDENE-5-DEOXY-D-XYLOFURANOSYL)-9-BORATABICYCLO[3.3.1]NONANE - ENANTIOSELECTIVE SYNTHESIS OF ALPHA-HYDROXY ACETALS WITH HIGH OPTICAL PURITIES

被引：15

作者：

CHO, BT

CHUN, YS

机构：

[1] Department of Chemisry, Hallym University, Chunchon

来源：

TETRAHEDRON-ASYMMETRY | 1994年 / 5卷 / 07期

关键词：

D O I：

10.1016/0957-4166(94)80142-8

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Asymmetric reduction of alpha-keto acetals with a chiral borohydride, potassiun 9-O-(1,2-isopropylidene-5-deoxy-alpha-D-xylofuranosyl)-9-boratabicyclo[3.3.1]nonane in THF at -78 degrees C provided the corresponding alpha-hydroxy acetals with 87-99% ee.

引用

页码：1147 / 1150

页数：4

共 18 条

[1]

APSIMON JW, 1986, TETRAHEDRON, V42, P231

[2]

BIANCHI D, 1989, TETRAHEDRON, V45, P869

[3]

BRANDANGE B, 1985, ACTA CHEM SCAND B, V39, P589

[4] SELECTIVE REDUCTIONS .40. A CRITICAL-EXAMINATION OF THE RELATIVE EFFECTIVENESS OF VARIOUS REDUCING AGENTS FOR THE ASYMMETRIC REDUCTION OF DIFFERENT CLASSES OF KETONES [J].