PHOTODYNAMIC INACTIVATION OF CANCER-CELLS INVITRO - EFFECT OF IRRADIATION TEMPERATURE AND DOSE FRACTIONATION

被引：48
作者：
MOAN, J [1 ]
CHRISTENSEN, T [1 ]
机构：
[1] NORSK HYDROS INST CANC RES,DEPT TISSUE CULTURE,OSLO,NORWAY
来源：
CANCER LETTERS | 1979年 / 6卷 / 06期
关键词：
D O I：
10.1016/S0304-3835(79)80090-7
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Human cancer cells in vitro (NHIK 3025), derived from a carcinoma in situ are inactivated when exposed to visible light in the presence of hematoporphyrin. Irradiation at 4°C results in much more efficient inactivation than irradiation at 37°C. Furthermore, a given total light dose is more efficient when it is fractionated than when it is given in a single exposure. These findings may be taken advantage of in future photochemotherapy of cancer. © 1979 Elsevier/North-Holland Scientific Publishers Ltd., All rights reserved.
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页码：331 / 335
页数：5
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