PHOTODYNAMIC INACTIVATION OF CANCER-CELLS INVITRO - EFFECT OF IRRADIATION TEMPERATURE AND DOSE FRACTIONATION

被引：48

作者：

MOAN, J ^{[1
]}

CHRISTENSEN, T ^{[1
]}

机构：

[1] NORSK HYDROS INST CANC RES,DEPT TISSUE CULTURE,OSLO,NORWAY

来源：

CANCER LETTERS | 1979年 / 6卷 / 06期

关键词：

D O I：

10.1016/S0304-3835(79)80090-7

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Human cancer cells in vitro (NHIK 3025), derived from a carcinoma in situ are inactivated when exposed to visible light in the presence of hematoporphyrin. Irradiation at 4°C results in much more efficient inactivation than irradiation at 37°C. Furthermore, a given total light dose is more efficient when it is fractionated than when it is given in a single exposure. These findings may be taken advantage of in future photochemotherapy of cancer. © 1979 Elsevier/North-Holland Scientific Publishers Ltd., All rights reserved.

引用

页码：331 / 335

页数：5

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