CONSERVED LINKAGE OF EARLY GROWTH-RESPONSE-4, ANNEXIN-4, AND TRANSFORMING GROWTH-FACTOR-ALPHA ON MOUSE CHROMOSOME-6

被引：14
作者：
BARROW, LL
SIMIN, K
JONES, JM
LEE, DC
MEISLER, MH
机构：
[1] UNIV MICHIGAN,DEPT HUMAN GENET,ANN ARBOR,MI 48109
[2] UNIV N CAROLINA,SCH MED,LINEBERGER CANC RES CTR,CHAPEL HILL,NC 27599
[3] UNIV N CAROLINA,SCH MED,DEPT MICROBIOL & IMMUNOL,CHAPEL HILL,NC 27599
来源：
GENOMICS | 1994年 / 19卷 / 02期
关键词：
D O I：
10.1006/geno.1994.1078
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
The mouse genes encoding early growth response 4 (Egr4), annexin IV (Anx4), and transforming growth factor alpha (Tgfa) have been mapped to a linkage group on mouse chromosome 6 that is conserved on human chromosome 2p11-p13. The genes are closely linked, with 0/215 recombinants between Anx4 and Tgfa and 1/215 recombinants between these genes and Egr4. The genes are located approximately 2 cM distal to mnd2, a mouse mutation causing neuromuscular disease. The results demonstrate that mnd2 is located at an internal position within this conserved linkage group. (C) 1994 Academic Press, Inc.
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页码：388 / 390
页数：3
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