NORMAL HUMAN TISSUES CONTAIN RNA AND ANTIGENS RELATED TO INFECTIOUS ADENOVIRUS TYPE-2

被引：29
|
作者：
JONES, KW [1 ]
KINROSS, J [1 ]
MAITLAND, N [1 ]
NORVAL, M [1 ]
机构：
[1] UNIV EDINBURGH,SCH MED,DEPT BACTERIOL,EDINBURGH EH8 9YL,MIDLOTHIAN,SCOTLAND
来源：
NATURE | 1979年 / 277卷 / 5694期
关键词：
D O I：
10.1038/277274a0
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Normal human tissues have been found to contain RNA which hybridises with four regions of the adenovirus type 2 genome, including one which contains the transforming gene(s) of this virus. The RNAs have also been extracted from gorilla organs, but not from those of chickens, suggesting that they are a feature of all normal higher primate tissues. Serological tests suggest that these homologous RNAs are translated into proteins connected with essentially normal and virus-infected cell functions. © 1979 Nature Publishing Group.
引用
收藏
页码：274 / 279
页数：6
相关论文
共 50 条
  • [31] BIDIRECTIONAL REPLICATION OF ADENOVIRUS TYPE-2 DNA
    HORWITZ, MS
    JOURNAL OF VIROLOGY, 1976, 18 (01) : 307 - 315
  • [32] ISOLATION AND PROPERTIES OF ADENOVIRUS TYPE-2 PROTEINASE
    TIHANYI, K
    BOURBONNIERE, M
    HOUDE, A
    RANCOURT, C
    WEBER, JM
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1993, 268 (03) : 1780 - 1785
  • [33] STRUCTURE AND COMPOSITION OF ADENOVIRUS TYPE-2 CORE
    BROWN, DT
    WESTPHAL, M
    BURLINGHAM, BT
    WINTERHOFF, U
    DOERFLER, W
    JOURNAL OF VIROLOGY, 1975, 16 (02) : 366 - 387
  • [34] MOLECULAR COMPOSITION OF THE ADENOVIRUS TYPE-2 VIRION
    VANOOSTRUM, J
    BURNETT, RM
    JOURNAL OF VIROLOGY, 1985, 56 (02) : 439 - 448
  • [35] PHYSICAL CHARACTERISTICS OF DNA OF ADENOVIRUS TYPE-2
    DOERFLER, W
    KLEINSCH.AK
    BULLETIN OF THE NEW YORK ACADEMY OF MEDICINE, 1970, 46 (06) : 459 - &
  • [36] ORGANIZATION AND EXPRESSION OF THE GENES OF ADENOVIRUS TYPE-2
    HERISSE, J
    BULLETIN DE L INSTITUT PASTEUR, 1982, 80 (03): : 197 - 244
  • [37] PROTEASE OF ADENOVIRUS TYPE-2 - PARTIAL CHARACTERIZATION
    BHATTI, AR
    WEBER, J
    VIROLOGY, 1979, 96 (02) : 478 - 485
  • [38] ANTIGENIC PROPERTIES OF THE SYNTHETIC PEPTIDES OF HEXON AND FIBER OF HUMAN ADENOVIRUS TYPE-2
    TARASSISHIN, LA
    BIOORGANICHESKAYA KHIMIYA, 1991, 17 (08): : 1141 - 1144
  • [39] EVIDENCE THAT ADENOVIRUS TYPE-2 CAN INFECT HUMAN-PLACENTA INVITRO
    FREUND, E
    ELLER, M
    KELLNER, K
    MCGUIRE, PM
    PLACENTA, 1981, 2 (03) : 265 - 270
  • [40] NONPERMISSIVITY OF HUMAN PERIPHERAL-BLOOD LYMPHOCYTES TO ADENOVIRUS TYPE-2 INFECTION
    HORVATH, J
    WEBER, JM
    JOURNAL OF VIROLOGY, 1988, 62 (01) : 341 - 345
12345