TRANSFORMING GROWTH FACTOR-BETA ACTIVITY IS POTENTIATED BY HEPARIN VIA DISSOCIATION OF THE TRANSFORMING GROWTH FACTOR-BETA ALPHA-2-MACROGLOBULIN INACTIVE COMPLEX

被引:229
作者
MCCAFFREY, TA
FALCONE, DJ
BRAYTON, CF
AGARWAL, LA
WELT, FGP
WEKSLER, BB
机构
[1] CORNELL UNIV,MED CTR,COLL MED,DEPT CELL BIOL & ANAT,NEW YORK,NY 10021
[2] CORNELL UNIV,MED CTR,COLL MED,DEPT PATHOL,NEW YORK,NY 10021
关键词
D O I
10.1083/jcb.109.1.441
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
引用
收藏
页码:441 / 448
页数:8
相关论文
共 66 条
[31]  
LIPPMAN LL, 1977, FED PROC, V36, P55
[32]   PROTEOLYTIC ACTIVATION OF LATENT TRANSFORMING GROWTH FACTOR-BETA FROM FIBROBLAST-CONDITIONED MEDIUM [J].
LYONS, RM ;
KESKIOJA, J ;
MOSES, HL .
JOURNAL OF CELL BIOLOGY, 1988, 106 (05) :1659-1665
[34]  
MASSAGUE J, 1985, J BIOL CHEM, V260, P2636
[35]  
MCCAFFREY TA, 1988, IN VITRO CELL DEV B, V24, P247
[36]   AGING AND ARTERIOSCLEROSIS - THE INCREASED PROLIFERATION OF ARTERIAL SMOOTH-MUSCLE CELLS ISOLATED FROM OLD RATS IS ASSOCIATED WITH INCREASED PLATELET-DERIVED GROWTH-FACTOR LIKE ACTIVITY [J].
MCCAFFREY, TA ;
NICHOLSON, AC ;
SZABO, PE ;
WEKSLER, ME ;
WEKSLER, BB .
JOURNAL OF EXPERIMENTAL MEDICINE, 1988, 167 (01) :163-174
[37]  
MIYAZONO K, 1988, J BIOL CHEM, V263, P6407
[38]   DEMONSTRATION OF STIMULATORY EFFECTS OF PLATELET-DERIVED GROWTH-FACTOR ON CULTIVATED RAT ARTERIAL SMOOTH-MUSCLE CELLS - DIFFERENCES BETWEEN CELLS FROM YOUNG AND ADULT ANIMALS [J].
NILSSON, J ;
KSIAZEK, T ;
HELDIN, CH ;
THYBERG, J .
EXPERIMENTAL CELL RESEARCH, 1983, 145 (02) :231-237
[39]  
NILSSON J, 1983, J CELL SCI, V64, P107
[40]  
OCONNORMCCOURT MD, 1987, J BIOL CHEM, V262, P14090