NEUROFOLLICULAR HAMARTOMA - A NEW HISTOGENETIC INTERPRETATION

被引：24
作者：
SANGUEZA, OP
REQUENA, L
机构：
[1] VET ADM MED CTR, PORTLAND, OR USA
[2] FDN JIMENEZ DIAZ, E-28040 MADRID, SPAIN
来源：
AMERICAN JOURNAL OF DERMATOPATHOLOGY | 1994年 / 16卷 / 02期
关键词：
HAMARTOMA; TRICHODISCOMA; FIBROFOLLICULOMA;
D O I：
10.1097/00000372-199404000-00008
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Neurofollicular hamartoma is a recently described entity characterized histopathologically by fascicles of spindle cells that are haphazardly arranged and laterally delimited by hyperplastic folliculo-sebaceous units. Immunohistochemical studies have shown the presence of a few S-100-positive cells scattered among the spindle cells. We report five cases of this peculiar entity and compare them to two examples of trichodiscomas. Both hamartomas were characterized by proliferations of spindle cells in close association with prominent folliculosebaceous units. Based on the clinical and histopathological findings, as well as the immunoperoxidase stains, we conclude that neurofollicular hamartomas are not different from trichodiscomas and fibrofolliculomas.
引用
收藏
页码：150 / 154
页数：5
相关论文
共 12 条
[1]  
ACERKMAN AB, 1993, NEOPLASMS FOLLICULAR, P245
[2]   NEUROFOLLICULAR HAMARTOMA - A LIGHT MICROSCOPIC AND IMMUNOHISTOCHEMICAL STUDY [J].
BARR, RJ ;
GOODMAN, MM .
JOURNAL OF CUTANEOUS PATHOLOGY, 1989, 16 (06) :336-341
[3]   HEREDITARY MULTIPLE FIBROFOLLICULOMAS WITH TRICHODISCOMAS AND ACROCHORDONS [J].
BIRT, AR ;
HOGG, GR ;
DUBE, WJ .
ARCHIVES OF DERMATOLOGY, 1977, 113 (12) :1674-1677
[4]  
CERIO R, 1989, BRIT J DERMATOL, V120, P197
[5]   THE TISSUE DISTRIBUTION OF FACTOR-XIIIA POSITIVE CELLS [J].
DERRICK, EK ;
BARKER, JNWN ;
KHAN, A ;
PRICE, ML ;
MACDONALD, DM .
HISTOPATHOLOGY, 1993, 22 (02) :157-162
[6]   MULTIPLE FIBROFOLLICULOMAS WITH TRICHODISCOMAS AND ACROCHORDONS [J].
FUJITA, WH ;
BARR, RJ ;
HEADLEY, JL .
ARCHIVES OF DERMATOLOGY, 1981, 117 (01) :32-35
[7]   FIBROUS PAPULE OF NOSE - A CLINICOPATHOLOGICAL STUDY [J].
GRAHAM, JH ;
SANDERS, JB ;
JOHNSON, WC ;
HELWIG, EB .
JOURNAL OF INVESTIGATIVE DERMATOLOGY, 1965, 45 (03) :194-&
[8]   NEUROFOLLICULAR HAMARTOMA - A CLINICOPATHOLOGICAL STUDY [J].
NOVA, MP ;
ZUNG, M ;
HALPERIN, A .
AMERICAN JOURNAL OF DERMATOPATHOLOGY, 1991, 13 (05) :459-462
[9]   TRICHODISCOMA - BENIGN TUMOR RELATED TO HAARSCHEIBE (HAIR DISK) [J].
PINKUS, H ;
COSKEY, R ;
BURGESS, GH .
JOURNAL OF INVESTIGATIVE DERMATOLOGY, 1974, 63 (02) :212-218
[10]  
REQUENA L, 1991, Journal of Dermatology (Tokyo), V18, P112
12