MECHANISTIC DEDUCTIONS FROM ISOTOPE EFFECTS IN MULTIREACTANT ENZYME MECHANISMS

被引：172

作者：

COOK, PF ^{[1
]}

CLELAND, WW ^{[1
]}

机构：

[1] UNIV WISCONSIN,DEPT BIOCHEM,MADISON,WI 53706

来源：

BIOCHEMISTRY | 1981年 / 20卷 / 07期

关键词：

D O I：

10.1021/bi00510a013

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

收藏

页码：1790 / 1796

页数：7

相关论文

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[3] USES AND LIMITATIONS OF MEASUREMENTS OF RATES OF ISOTOPIC EXCHANGE AND INCORPORATION IN CATALYZED REACTIONS
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[4] Cleland W W, 1979, Methods Enzymol, V63, P103
[5] Cleland W W, 1980, Methods Enzymol, V64, P104
[6] PARTITION ANALYSIS AND CONCEPT OF NET RATE CONSTANTS AS TOOLS IN ENZYME-KINETICS
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[7] CLELAND WW, 1977, ISOTOPE EFFECTS ENZY, P153
[8] PH VARIATION OF ISOTOPE EFFECTS IN ENZYME-CATALYZED REACTIONS .2. ISOTOPE-DEPENDENT STEP NOT PH DEPENDENT - KINETIC MECHANISM OF ALCOHOL-DEHYDROGENASE
COOK, PF
CLELAND, WW
[J]. BIOCHEMISTRY, 1981, 20 (07) : 1805 - 1816
[9] PH VARIATION OF ISOTOPE EFFECTS IN ENZYME-CATALYZED REACTIONS .1. ISOTOPE-DEPENDENT AND PH-DEPENDENT STEPS THE SAME
COOK, PF
CLELAND, WW
[J]. BIOCHEMISTRY, 1981, 20 (07) : 1797 - 1805
[10] PRIMARY AND SECONDARY DEUTERIUM-ISOTOPE EFFECTS ON EQUILIBRIUM-CONSTANTS FOR ENZYME-CATALYZED REACTIONS
COOK, PF
BLANCHARD, JS
CLELAND, WW
[J]. BIOCHEMISTRY, 1980, 19 (21) : 4853 - 4858