SYNTHESIS OF NOVEL IMIDAZOLE-CONTAINING DNA MINOR GROOVE BINDING OLIGOPEPTIDES RELATED TO THE ANTIVIRAL ANTIBIOTIC NETROPSIN

被引:77
|
作者
KROWICKI, K [1 ]
LOWN, JW [1 ]
机构
[1] UNIV ALBERTA,DEPT CHEM,EDMONTON T6G 2G2,ALBERTA,CANADA
来源
JOURNAL OF ORGANIC CHEMISTRY | 1987年 / 52卷 / 16期
关键词
D O I
10.1021/jo00392a001
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
引用
收藏
页码:3493 / 3501
页数:9
相关论文
共 50 条
  • [21] Human DNA-topoisomerase I activity is affected by bis-netropsin's binding to DNA minor groove
    Sukhanova, A
    Grokhovsky, S
    Zhuze, A
    Roper, D
    Bronstein, I
    BIOCHEMISTRY AND MOLECULAR BIOLOGY INTERNATIONAL, 1998, 44 (05): : 997 - 1010
  • [22] Synthesis of novel DNA binding agents: indole-containing analogues of bis-netropsin
    Khalaf, AI
    Pitt, AR
    Scobie, M
    Suckling, CJ
    Urwin, J
    Waigh, RD
    Fishleigh, RV
    Young, SC
    JOURNAL OF CHEMICAL RESEARCH-S, 2000, (06): : 264 - 265
  • [23] DESIGN, SYNTHESIS, AND DNA-BINDING PROPERTIES OF C-TERMINUS TRUNCATED AND IMIDAZOLE-CONTAINING ANALOGS OF DISTAMYCIN
    PRETI, C
    TROUTMAN, MV
    LEE, M
    FORROW, S
    HARTLEY, JA
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1993, 206 : 121 - MEDI
  • [24] Hx, a Novel Fluorescent, Minor Groove and Sequence Specific Recognition Element: Design, Synthesis, and DNA Binding Properties of p-Anisylbenzimidazole-imidazole/pyrrole-Containing Polyamides
    Chavda, Sameer
    Liu, Yang
    Babu, Balaji
    Davis, Ryan
    Sielaff, Alan
    Ruprich, Jennifer
    Westrate, Laura
    Tronrud, Christopher
    Ferguson, Amanda
    Franks, Andrew
    Tzou, Samuel
    Adkins, Chandler
    Rice, Toni
    Mackay, Hilary
    Kluza, Jerome
    Tahir, Sharjeel A.
    Lin, Shicai
    Kiakos, Konstantinos
    Bruce, Chrystal D.
    Wilson, W. David
    Hartley, John A.
    Lee, Moses
    BIOCHEMISTRY, 2011, 50 (15) : 3127 - 3136
  • [25] Hx, a novel fluorescent, minor groove and sequence specific recognition element: Design, synthesis, and DNA binding properties of p-anisylbenzimidazole imidazole/pyrrole-containing polyamides
    Chavda, Sameer
    Liu, Yang
    Babu, Balaji
    Davis, Ryan
    Sielaff, Alan
    Ruprich, Jennifer
    Westrate, Laura
    Tronrud, Christopher
    Ferguson, Amanda
    Franks, Andrew
    Tzou, Samuel
    Adkins, Chandler
    Rice, Toni
    Mackay, Hilary
    Kluza, Jerome
    Tahir, Sharjeel A.
    Lin, Shicai
    Kiakos, Konstantinos
    Bruce, Chrystal D.
    Wilson, W. David
    Hartley, John A.
    Lee, Moses
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2011, 242
  • [26] Synthesis and Characterization of DNA Minor Groove Binding Alkylating Agents
    Iyer, Prema
    Srinivasan, Ajay
    Singh, Sreelekha K.
    Mascara, Gerard P.
    Zayitova, Sevara
    Sidone, Brian
    Fouquerel, Elise
    Svilar, David
    Sobol, Robert W.
    Bobola, Michael S.
    Silber, John R.
    Gold, Barry
    CHEMICAL RESEARCH IN TOXICOLOGY, 2013, 26 (01) : 156 - 168
  • [27] Synthesis and binding studies of a new DNA minor groove binder
    Clark, CI
    White, JM
    Kelly, DP
    Martin, RF
    Lobachevsky, P
    AUSTRALIAN JOURNAL OF CHEMISTRY, 1998, 51 (03) : 243 - 247
  • [28] Sequence-specific DNA minor groove binders. Design and synthesis of netropsin and distamycin analogues
    Bailly, C
    Chaires, JB
    BIOCONJUGATE CHEMISTRY, 1998, 9 (05) : 513 - 538
  • [29] Fluorous synthesis of minor groove binding agents related to distamycin
    Mamidyala, Sreernan K.
    Firestine, Steven M.
    TETRAHEDRON LETTERS, 2006, 47 (42) : 7431 - 7434
  • [30] Sequence-specific DNA minor groove binders. Design and synthesis of netropsin and distamycin analogues
    INSERM U-124, Lab. Pharmacologie Antitumorale M., IRCL, Place de Verdun, 59045 Lille, France
    不详
    Bioconjugate Chemistry, 9 (05): : 513 - 538