The arterial load in pulmonary hypertension

被引:153
作者
Saouti, N. [1 ]
Westerhof, N. [1 ,2 ]
Postmus, P. E. [1 ]
Vonk-Noordegraaf, A. [1 ]
机构
[1] Vrije Univ Amsterdam, Med Ctr, Dept Pulm Dis, Boelelaan 1117, NL-1081 HV Amsterdam, Netherlands
[2] Vrije Univ Amsterdam, Med Ctr, Inst Cardiovasc Res, Dept Physiol, NL-1081 HV Amsterdam, Netherlands
关键词
Compliance; pulmonary hypertension; resistance; systemic circulation; Windkessel;
D O I
10.1183/09059180.00002210
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
The anatomical differences between the pulmonary and systemic arterial system are the main cause of the difference in distribution of compliance. In the pulmonary arterial system compliance is distributed over the entire arterial system, and stands at the basis of the constancy of the RC-time. This distribution depends on the number of peripheral vessels, which is similar to 8-10 times more in the pulmonary system than the systemic tree. In the systemic arterial tree the compliance is mainly located in the aorta (80% of total compliance in thoracic-abdominal aorta). The constant RC-time in the pulmonary bed results in proportionality of systolic and diastolic pressure with mean pressure and, in turn, in the constant ratio of oscillatory and mean power.Y
引用
收藏
页码:197 / 203
页数:7
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