Legionnaires' disease

被引:2
作者
Erdogan, Haluk [1 ]
机构
[1] Baskent Univ, Alanya Arastirma & Uygulama Merkeri, Knteksiyon Hastaliklari & Klin Mikrobiyol ABD, Ankara, Turkey
关键词
Legionnaires' disease; Legionella pneumophila; Legionella spp;
D O I
10.4274/mjima.2018.2
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Legionnaires disease is a severe from of pneumonia caused by Legionella species which arc ubiquitious in both natural and man-made environments. It has high morbidity and case fetality rates. The disease is acquired by aspiration of water or inhalation of aerosols containing the bactena from environmental sources. Early diagnosis and appropriate treatment are important factors in determining prognosis. Clinical and laboratory predictors will not reliably identify cases of legionnaires disease, therefore the diagnosis of Legionnaires' disease requires specific diagnostic tests. The diagnosis of Legionnaires' disease is made by culture, Legionella urinary antigenaria, polymeras ion, or serologic analyses. Isolation of Legionella from clinical samples is the gold standart for diagnosing Legioimaire's disease. Legionella urinary antigen tests are easy and useful for early diagnosis of Legionnaires' disease. Flouroquinolones, macrolides and doxycicline are drugs of choice. Legionnaires' disease is considered a preventable illness since it is possible to control and remove the bacteria in reserviors. In Turkey, travel-associated Legionnaires' disease has a specific surveillance programe since 1996. After the year of 2015, it became mandatory to take environmental cultures for Legionella from the hospital water systems. The aim of this review is to raise awereness for legionollosis and to summarize the current literature.
引用
收藏
页数:27
相关论文
共 81 条
[11]   OROPHARYNGEAL COLONIZATION WITH LEGIONELLA-PNEUMOPHILA [J].
BRIDGE, JA ;
EDELSTEIN, PH .
JOURNAL OF CLINICAL MICROBIOLOGY, 1983, 18 (05) :1108-1112
[12]   Isolation of ciprofloxacin-resistant Legionella pneumophila in a patient with severe pneumonia [J].
Bruin, Jacob P. ;
Koshkolda, Tetyana ;
IJzerman, Ed P. F. ;
Lueck, Christian ;
Diederen, Bram M. W. ;
Den Boer, Jeroen W. ;
Mouton, Johan W. .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2014, 69 (10) :2869-2871
[13]   Investigation of Legionella pneumophila and free living amoebas in the domestic hot water systems in Istanbul [J].
Burak, Dilara Meryem ;
Zeybek, Zuhal .
TURKISH JOURNAL OF BIOLOGY, 2011, 35 (06) :679-685
[14]   Quinolones versus macrolides in the treatment of legionellosis: a systematic review and meta-analysis [J].
Burdet, C. ;
Lepeule, R. ;
Duval, X. ;
Caseris, M. ;
Rioux, C. ;
Lucet, J. -C. ;
Yazdanpanah, Y. .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2014, 69 (09) :2354-2360
[15]   Microbiology and Epidemiology of Legionnaire's Disease [J].
Burillo, Almudena ;
Luisa Pedro-Botet, Maria ;
Bouza, Emilio .
INFECTIOUS DISEASE CLINICS OF NORTH AMERICA, 2017, 31 (01) :7-+
[16]   Transverse myelitis and acute motor sensory axonal neuropathy due to Legionella pneumophila: A case report [J].
Canpolat, Mehmet ;
Kumandas, Sefer ;
Yikilmaz, Ali ;
Gumus, Hakan ;
Koseoglu, Emel ;
Poyrazoglu, Hatice Gamze ;
Kose, Mehmet ;
Per, Huseyin .
PEDIATRICS INTERNATIONAL, 2013, 55 (06) :778-782
[17]  
Casini B, 2015, CLIN INFECT DIS, V60, P1596
[18]   Application of Hydrogen Peroxide as an Innovative Method of Treatment for Legionella Control in a Hospital Water Network [J].
Casini, Beatrice ;
Aquino, Francesco ;
Totaro, Michele ;
Miccoli, Mario ;
Galli, Irio ;
Manfredini, Laura ;
Giustarini, Carlo ;
Costa, Anna Laura ;
Tuvo, Benedetta ;
Valentini, Paola ;
Privitera, Gaetano ;
Baggiani, Angelo .
PATHOGENS, 2017, 6 (02)
[19]   Antimicrobial strategy for severe community-acquired legionnaires' disease: a multicentre retrospective observational study [J].
Cecchini, Jerome ;
Tuffet, Samuel ;
Sonneville, Romain ;
Fartoukh, Muriel ;
Mayaux, Julien ;
Roux, Damien ;
Kouatchet, Achille ;
Boissier, Florence ;
Tchir, Martial ;
Thyrault, Martial ;
Maury, Eric ;
Jochmans, Sebastien ;
Dessap, Armand Mekontso ;
Brun-Buisson, Christian ;
de Prost, Nicolas .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2017, 72 (05) :1502-1509
[20]   Effect of UV irradiation (253.7 nm) on free Legionella and Legionella associated with its amoebae hosts [J].
Cervero-Arago, Silvia ;
Sommer, Regina ;
Araujo, Rosa M. .
WATER RESEARCH, 2014, 67 :299-309