JUNCTIONAL MODULATION IN MOUSE EMBRYONAL CARCINOMA-CELLS BY FAB FRAGMENTS OF RABBIT ANTI-EMBRYONAL CARCINOMA CELL SERUM

被引：21

作者：

DUNIA, I

NICOLAS, JF

JAKOB, H

BENEDETTI, EL

JACOB, F

机构：

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1979年 / 76卷 / 07期

关键词：

D O I：

10.1073/pnas.76.7.3387

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Mouse embryonal carcinoma PCC4 cells are connected by extensive gap and tight junctions. When the cells are incubated in a medium containing Fab fragments against embryonal carcinoma F9 cells, they round up and a process of junctional removal is initiated. In particular, gap junctions are internalized and after 30 hr of incubation with the anti-F9 Fab fragments both tight and gap junctions are no longer present at the cell surface; however, the cells are still in contact by means of small attachment sites.

引用

页码：3387 / 3391

页数：5

共 28 条

[1] APPEARANCE AND STRUCTURE OF INTERCELLULAR CONNECTIONS DURING ONTOGENY OF RABBIT OVARIAN FOLLICLE WITH PARTICULAR REFERENCE TO GAP JUNCTIONS [J].