CHEMICAL SYNTHESIS OF OLIGORIBONUCLEOTIDES CONTAINING 2-AMINOPURINE - SUBSTRATES FOR THE INVESTIGATION OF RIBOZYME FUNCTION

被引：39
作者：
DOUDNA, JA
SZOSTAK, JW
RICH, A
USMAN, N
机构：
[1] MIT,DEPT BIOL,CAMBRIDGE,MA 02139
[2] MASSACHUSETTS GEN HOSP,DEPT MOLEC BIOL,BOSTON,MA 02114
来源：
JOURNAL OF ORGANIC CHEMISTRY | 1990年 / 55卷 / 21期
关键词：
D O I：
10.1021/jo00308a003
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
: The chemical synthesis of a fully protected ribonucleoside phosphoramidite, containing 2-aminopurine as the base component, and its incorporation into short oligoribonucleotides as substrates for an engineered ribo-zyme from Tetrahymena is described. © 1990, American Chemical Society. All rights reserved.
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页码：5547 / 5549
页数：3
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