THE CERAD EXPERIENCE .8. NEUROIMAGING NEUROPATHOLOGY CORRELATES OF TEMPORAL-LOBE CHANGES IN ALZHEIMERS-DISEASE

被引：35
作者：
DAVIS, PC
GEARING, M
GRAY, L
MIRRA, SS
MORRIS, JC
EDLAND, SD
LIN, T
HEYMAN, A
机构：
[1] EMORY UNIV,SCH MED,ATLANTA,GA
[2] ATLANTA VET AFFAIRS MED CTR,DECATUR,GA
[3] DUKE UNIV,MED CTR,DURHAM,NC
[4] WASHINGTON UNIV,ST LOUIS,MO
[5] UNIV WASHINGTON,SEATTLE,WA 98195
来源：
NEUROLOGY | 1995年 / 45卷 / 01期
关键词：
D O I：
10.1212/WNL.45.1.178
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
We compared premortem neuroimaging findings with neuropathologic evidence of temporal lobe atrophy in 20 patients with Alzheimer's disease (AD) confirmed by autopsy. There were significant correlations between temporal horn enlargement observed by neuroimaging and hippocampal atrophy at autopsy, and between the overall cerebral atrophy severity on neuroimaging and scores on the Mini-Mental State Examination, This report confirms previous studies correlating temporal lobe atrophy on neuroimaging with a clinical diagnosis of AD, although more precise neuroimaging techniques are needed for use in multicenter studies of AD.
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页码：178 / 179
页数：2
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