ADHESION RECEPTORS IN LYMPHOCYTE-ACTIVATION

被引:96
作者
COLLINS, TL
KASSNER, PD
BIERER, BE
BURAKOFF, SJ
机构
[1] HARVARD UNIV, SCH MED, DIV PEDIAT ONCOL, BOSTON, MA 02115 USA
[2] HARVARD UNIV, SCH MED, DEPT PEDIAT, BOSTON, MA 02115 USA
[3] BRIGHAM & WOMENS HOSP, DANA FARBER CANC INST, BOSTON, MA USA
关键词
D O I
10.1016/0952-7915(94)90117-1
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The past several years have seen significant progress in understanding the role of T lymphocyte coreceptors in adhesion and activation. New insights have been gained in several areas: the avidity regulation of beta 1 and beta 2 integrins and their role in signal transduction; the regulation of CD8 avidity; the role of Lck in CD4 coreceptor activity; and the novel role for CD2 adhesion in the T cell antigen response.
引用
收藏
页码:385 / 393
页数:9
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