MICHAEL ADDITIONS TO ACRYLONITRILE, METHYL ACRYLATE AND METHYL VINYL KETONE TO NB-BENZYLIDENETRYPTOPHAN METHYL-ESTER

被引：1

作者：

BRANA, MF

GARRIDO, M

RODRIGUEZ, MLL

MORCILLO, MJ

机构：

[1] Departamento de Química Orgánica I, Facultad de Ciencias Químicas, Universidad Complutense, Madrid

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1990年 / 27卷 / 02期

关键词：

D O I：

10.1002/jhet.5570270246

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Michael addition to methyl acrylate and methyl vinyl ketone of Nb‐benzylidene‐L‐tryptophan methyl ester 1 gave 2‐(3‐indolylmethyl)glutamic dimethyl ester 2a and α‐(3‐oxobutyl)tryptophan methyl ester 2b respectively. Addition to acrylonitrile of 1 yielded α,Na‐dicyanoethyltryptophan methyl ester 3. Copyright © 1990 Journal of Heterocyclic Chemistry

引用

页码：357 / 358

页数：2

共 11 条

[1]

BEY P, 1907, TETRAHEDRON LETT, V17, P145

[2]

BRANA MF, 1986, AN QUIM C-ORG BIOQ, V82, P266

[3]

BRANA MF, 1987, HETEROCYCLES, V26, P2139

[4]

BRANA MF, 1987, HETEROCYCLES, V26, P95