Suv39h1 links the SUMO pathway to constitutive heterochromatin

被引：5
|
作者：
Maison, Christele [1 ,2 ]
Quivy, Jean-Pierre [1 ,2 ]
Almouzni, Genevieve [1 ,2 ]
机构：
[1] PSL Res Univ, Inst Curie, CNRS, UMR3664,Equipe Labellisee Ligue Canc, Paris, France
[2] UPMC Univ Paris 06, Sorbonne Univ, CNRS, UMR3664, Paris, France
来源：
MOLECULAR & CELLULAR ONCOLOGY | 2016年 / 3卷 / 06期
关键词：
Heterochromatin; HP1; nuclear organization; SUMO pathway; suv39h1;
D O I：
10.1080/23723556.2016.1225546
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
The Suv39h lysine methyltransferases, known as key enzymes responsible for histone H3 lysine 9 methylation, are critical for heterochromatin protein 1 enrichment at constitutive heterochromatin. Our recent findings reveal a new role for the Suv39h1 paralog that links it to SUMO pathway function at constitutive heterochromatin.
引用
收藏
页数：2
相关论文
共 50 条
  • [1] The methyltransferase Suv39h1 links the SUMO pathway to HP1α marking at pericentric heterochromatin
    Christèle Maison
    Delphine Bailly
    Jean-Pierre Quivy
    Geneviève Almouzni
    Nature Communications, 7
  • [2] The methyltransferase Suv39h1 links the SUMO pathway to HP1α marking at pericentric heterochromatin
    Maison, Christele
    Bailly, Delphine
    Quivy, Jean-Pierre
    Almouzni, Genevieve
    NATURE COMMUNICATIONS, 2016, 7
  • [3] RNA dependent stabilization of SUV39H1 at constitutive heterochromatin
    Johnson, W. L.
    Yewdell, W. T.
    McNulty, S. M.
    Duda, Z.
    O'Neill, R. J.
    Sullivan, B. A.
    Straight, A. F.
    MOLECULAR BIOLOGY OF THE CELL, 2016, 27
  • [4] RNA-dependent stabilization of SUV39H1 at constitutive heterochromatin
    Johnson, Whitney L.
    Yewdell, William T.
    Bell, Jason C.
    McNulty, Shannon M.
    Duda, Zachary
    O'Neill, Rachel J.
    Sullivan, Beth A.
    Straight, Aaron F.
    ELIFE, 2017, 6
  • [5] A glue for heterochromatin maintenance: stable SUV39H1 binding to heterochromatin is reinforced by the SET domain
    Krouwels, IM
    Wiesmeijer, K
    Abraham, TE
    Molenaar, C
    Verwoerd, NP
    Tanke, HJ
    Dirks, RW
    JOURNAL OF CELL BIOLOGY, 2005, 170 (04): : 537 - 549
  • [6] Direct RNA binding stabilizes the histone methyltransferase SUV39H1 at pericentric heterochromatin.
    Johnson, W. L.
    Yewdell, W. T.
    Straight, A. F.
    MOLECULAR BIOLOGY OF THE CELL, 2014, 25
  • [7] Self-interaction of heterochromatin protein 1 is required for direct binding to histone methyltransferase, SUV39H1
    Yamamoto, K
    Sonoda, M
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2003, 301 (02) : 287 - 292
  • [8] SIRT1 regulates the histone methyl-transferase SUV39H1 during heterochromatin formation
    Vaquero, Alejandro
    Scher, Michael
    Erdjument-Bromage, Hediye
    Tempst, Paul
    Serrano, Lourdes
    Reinberg, Danny
    NATURE, 2007, 450 (7168) : 440 - 444
  • [9] SIRT1 regulates the histone methyl-transferase SUV39H1 during heterochromatin formation
    Alejandro Vaquero
    Michael Scher
    Hediye Erdjument-Bromage
    Paul Tempst
    Lourdes Serrano
    Danny Reinberg
    Nature, 2007, 450 : 440 - 444
  • [10] Overexpression of histone methyltransferases SUV39H1 and SUV39H2 in hepatocellular carcinoma
    Wong, Chun-Ming
    Ng, Irene
    CANCER RESEARCH, 2009, 69
12345