The modification and assembly of proteins in the endoplasmic reticulum

被引：119
作者：
Gaut, James R. [1 ]
Hendershot, Linda M. [1 ]
机构：
[1] St Jude Childrens Res Hosp, Dept Tumor Cell Biol, Memphis, TN 38105 USA
来源：
CURRENT OPINION IN CELL BIOLOGY | 1993年 / 5卷 / 04期
关键词：
D O I：
10.1016/0955-0674(93)90127-C
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Proteins fold and assemble in the endoplasmic reticulum in an environment that is very different from the cytosol. The presence of relatively high concentrations of calcium, an oxidizing state, ATP and lumenal proteins are all important in mediating these events.
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页码：589 / 595
页数：7
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共 71 条
[1]  
AHLUWALIA N, 1992, J BIOL CHEM, V267, P10914
[2]   VESICLES AND CISTERNAE IN THE TRANS GOLGI-APPARATUS OF HUMAN-FIBROBLASTS ARE ACIDIC COMPARTMENTS [J].
ANDERSON, RGW ;
PATHAK, RK .
CELL, 1985, 40 (03) :635-643
[3]   A VIEW OF ACIDIC INTRACELLULAR COMPARTMENTS [J].
ANDERSON, RGW ;
ORCI, L .
JOURNAL OF CELL BIOLOGY, 1988, 106 (03) :539-543
[4]   S-CYCLOPHILIN IS RETAINED INTRACELLULARLY VIA A UNIQUE COOH-TERMINAL SEQUENCE AND COLOCALIZES WITH THE CALCIUM STORAGE PROTEIN CALRETICULIN [J].
ARBER, S ;
KRAUSE, KH ;
CARONI, P .
JOURNAL OF CELL BIOLOGY, 1992, 116 (01) :113-125
[5]   A PEPTIDE SEQUENCE CONFERS RETENTION AND RAPID DEGRADATION IN THE ENDOPLASMIC-RETICULUM [J].
BONIFACINO, JS ;
SUZUKI, CK ;
KLAUSNER, RD .
SCIENCE, 1990, 247 (4938) :79-82
[6]   ROLE OF ATP AND DISULFIDE BONDS DURING PROTEIN FOLDING IN THE ENDOPLASMIC-RETICULUM [J].
BRAAKMAN, I ;
HELENIUS, J ;
HELENIUS, A .
NATURE, 1992, 356 (6366) :260-262
[7]   MANIPULATING DISULFIDE BOND FORMATION AND PROTEIN FOLDING IN THE ENDOPLASMIC-RETICULUM [J].
BRAAKMAN, I ;
HELENIUS, J ;
HELENIUS, A .
EMBO JOURNAL, 1992, 11 (05) :1717-1722
[8]  
CLAIRMONT CA, 1992, J BIOL CHEM, V267, P3983
[9]   EFFICIENT DISSOCIATION OF THE P88 CHAPERONE FROM MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-I MOLECULES REQUIRES BOTH BETA-2-MICROGLOBULIN AND PEPTIDE [J].
DEGEN, E ;
COHENDOYLE, MF ;
WILLIAMS, DB .
JOURNAL OF EXPERIMENTAL MEDICINE, 1992, 175 (06) :1653-1661
[10]   OVEREXPRESSION OF GRP78 MITIGATES STRESS INDUCTION OF GLUCOSE REGULATED PROTEINS AND BLOCKS SECRETION OF SELECTIVE PROTEINS IN CHINESE-HAMSTER OVARY CELLS [J].
DORNER, AJ ;
WASLEY, LC ;
KAUFMAN, RJ .
EMBO JOURNAL, 1992, 11 (04) :1563-1571
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