Antioxidant, alpha-amylase inhibitory and antiglycation activity of Berberis royleana roots

In the current research work, the plant roots were investigated for their antioxidant, alpha-amylase inhibitory and antiglycation activities. The results obtained revealed that the maximum antioxidant activity 1.984% was exhibited by an aqueous fraction at a concentration of 1mg/ml. The maximum alpha-amylase inhibition was exhibited by ethyl acetate 1.864% and n-hexane fraction 1.483% at a concentration of 1mg/ml while the chloroform and aqueous fraction exhibits minimum inhibition 0.075% and 0.073% at 0.613mg/ml concentration. The chloroform fraction exhibited maximum antiglycation potential of 12% at 0.5 mu g/ml while the minimum potential was 5.5% exhibited by ethyl acetate fraction at a concentration of 1 mu g/ml. The results obtained revealed the medicinal importance of the plant and will help the researchers to exploit the phytochemicals for antioxidant, alpha-amylase inhibitory and antiglycation activities.