Detection Rate of Rapid Antigen Test for Pandemic Influenza A (H1N1 2009)

被引：1
作者：
Kim, Young Keun [1 ]
Kim, Hyo Youl [1 ]
Uh, Young [2 ]
Chun, Jin-Kyong [3 ]
机构：
[1] Yonsei Univ, Wonju Coll Med, Dept Internal Med, Wonju, South Korea
[2] Yonsei Univ, Wonju Coll Med, Dept Lab Med, Wonju, South Korea
[3] Yonsei Univ, Wonju Coll Med, Dept Pediat, Wonju, South Korea
来源：
INFECTION AND CHEMOTHERAPY | 2010年 / 42卷 / 02期
关键词：
Influenza A; Pandemic; Reverse Transcriptase Polymerase Chain Reaction; Rapid Antigen Test; Sensitivity;
D O I：
10.3947/ic.2010.42.2.95
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
There are few datas on the diagnostic accuracy of rapid antigen test for pandemic influenza A (H1N1). We evaluated the performance of rapid antigen test for the diagnosis of pandemic influenza A (H1N1). During the period from 21 August 2009 to 20 September 2009, 451 patients with influenza-like symptom underwent the rapid antigen test (SD Influenza Antigen, Standard Diagnostics, Yongin, Korea) and real-time reverse transcriptase-polymerase chain reaction (rRT-PCR) at the same time. Rapid antigen test results were positive for 65 of 90 patients with the positive results for pandemic influenza A (H1N1) on rRT-PCR assay. The sensitivity of the rapid antigen test was 72.2% (95% CI, 61.8-81.1) and the specificity was 100% (95% CI, 99.0-100). The positive predictive value was 100% (95% CI, 94.5-100) and negative predictive value was 93.5% (95% CI, 90.6-95.8).
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页码：95 / 98
页数：4
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