HOLOPROSENCEPHALY AND POLYDACTYLY - A POSSIBLE EXPRESSION OF THE HYDROLETHALUS SYNDROME

被引：34

作者：

BACHMAN, H ^{[1
]}

CLARK, RD ^{[1
]}

SALAHI, W ^{[1
]}

机构：

[1] UNIV CALIF LOS ANGELES,LOS ANGELES CTY HARBOR MED CTR,DEPT PATHOL,TORRANCE,CA 90502

来源：

JOURNAL OF MEDICAL GENETICS | 1990年 / 27卷 / 01期

关键词：

D O I：

10.1136/jmg.27.1.50

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

We report two fetuses with hydrocephalus, features of holoprosencephaly, and postaxial polydactyly born to a consanguineous Mexican-American couple. The phenotype is consistent with the hydrolethalus syndrome, although holoprosencephaly has not previously been seen in this condition. We believe other similar cases with a trisomy 13 phenotype but normal chromosomes may also have the hydrolethalus syndrome.

引用

页码：50 / 52

页数：3

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