STUDY TO KNOW VITAMIN D AND CALCIUM SUPPLEMENTS ROLE IN REUNION OF FRACTURES

Objective: To investigate vitamin D and calcium supplementation effects in the case of non-consigmenting of the fracture nonunion. Study design: non-randomized intervention study. Place and duration of the study: This study was conducted from January 2015 to January 2016 for the period of one year in Lahore General Hospital. Methodology: Total fourteen patients were selected for study. vitamin D, Serum calcium and parathyroid hormone levels (PTH) were checked in all selected patients. 2 main groups of patients were made. In Group 1, only vitamin D and calcium were given, Group 2 was divided into two subgroups. In the subgroup (A), surgical support was provided with vitamin D and calcium application, and the second subgroup (B) was operated without supplementation. Calcium and Vitamin D supplement were applied in Tab Qalsan, 1 OD and 0.5 mu g tab Bone One. The events were performed on a monthly basis. Until the fractures were combined vitamin D and Calcium supplementation continued. Findings: Males were 85.71% in this study. 37.71 was the average age. The mean duration of the lesion applied with pseudoarthrosis was 11.4 months in our study. Of the 14 patients in total, 5 were treated with only calcium and D3 vitamins. Two patients received calcium and D3 vitamin therapy. Seven patients underwent surgery without D3 and calcium vitamins. serum calcium low levels in 2 patients, low serum D vitamins in 6 patients, and parathyroid hormone levels low in 1 patient. The 95% confidence interval, which is a endocrine or metabolic abnormality in patients with pseudoarthrosis, increased from 27.01% to 73.02% according to the Modified Wald method. All the patients got a bone marrow. 6 months was the mean duration of the union. Conclusion: 6 of our patients with long bone pseudoarthrosis had Vitamin D deficiency. Calcium and vitamin D were coordinated with oral replacement. This suggests that metabolic supplements play a role in the fusion of fractures after surgical intervention.