Inflammatory myofibroblastic tumor of the lung

被引：43

作者：

Khatri, Akshay ^{[1
]}

Agrawal, Abhinav ^{[2
]}

Sikachi, Rutuja R. ^{[2
]}

Mehta, Dhruv ^{[3
]}

Sahni, Sonu ^{[4
]}

Meena, Nikhil ^{[5
]}

机构：

[1] Westchester Med Ctr, Dept Med, Valhalla, NY USA

[2] Northwell Hlth, Div Pulm Crit Care & Sleep Med, Zucker Sch Med Hofstra Northwell, New Hyde Pk, NY USA

[3] Westchester Med Ctr, Div Gastroenterol, Valhalla, NY USA

[4] Touro Coll Osteopath Med, Dept Primary Care, New York, NY USA

[5] Univ Arkansas, Div Pulm Crit Care & Sleep Med, Little Rock, AR 72204 USA

来源：

ADVANCES IN RESPIRATORY MEDICINE | 2018年 / 86卷 / 01期

关键词：

inflammatory myofibroblastic tumor of the lung (IMT); inflammatory pseudo-tumor (IPT); pulmonary neoplasm; ALK; bronchoscopy;

D O I：

10.5603/ARM.2018.0007

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

Inflammatory myofibroblastic tumors (IMT) of the lung, first reported in 1939, are considered a subset of inflammatory pseudo-tumors. They are a distinctive lesions composed of myofibroblastic spindle cells accompanied by an inflammatory infiltrate of plasma cells, lymphocytes, and eosinophils. IMTs may be benign, invade surrounding structures, undergo malignant transformation, recur or may even metastasize. They can occur due to a genetic mutation or can occur secondary to infectious or autoimmune diseases. Patients may be asymptomatic, or present with cough, hemoptysis, dyspnea, pleuritic pain, constitutional symptoms or pneumonia. In this article we review the pathophysiology, genetics, clinical presentation, imaging findings of IMT of the lung. We also discuss the various surgical and non-surgical treatment options and the prognosis associated with this disease.

引用

页码：27 / 35

页数：9

共 107 条

[61] Inflammatory myofibroblastic tumors [J].