SYNTHESIS AND STRUCTURAL ASSIGNMENT OF CERTAIN PYRIMIDO[1,2-A]BENZIMIDAZOLE DERIVATIVES

被引：0

作者：

AHMED, SG

AHMED, AHN

OMAR, NM

ELGENDY, MA

机构：

[1] UNIV ASSIUT,FAC PHARM,DEPT ORGAN PHARMACEUT CHEM,ASSIUT,EGYPT

[2] UNIV ASSIUT,FAC PHARM,DEPT MED PHARMACEUT CHEM,ASSIUT,EGYPT

来源：

JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY | 1993年 / 57卷 / 04期

关键词：

PYRIMIDO[1,2-A]BENZIMIDAZOLES; BENZIMIDAZOLIUM; PERCHLORATES;

D O I：

暂无

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The pyrimido[1,2-a]benzimidazole derivatives compounds 1-8 were synthesized through cyclocondensation of 2-aminobenzimidazole with the appropriate benzsubstituted benzoylacetone by fusion at 150-170-degrees-C for 5 h. Quaternary salts compounds 9-22 were obtained by quaternization of compounds 1-8 with dimethyl or diethyl sulfate and subsequent isolation as the relatively insoluble perchlorate salts. Assignment and confirmation of the structures of the newly synthesized compounds were based upon elemental microanalyses and other spectral evidence.

引用

页码：363 / 370

页数：8

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