IDENTIFICATION OF A SPECIFIC BINDING-SITE FOR K+ CHANNEL OPENERS IN RAT AORTA

被引：0

作者：

QUAST, U ^{[1
]}

BRAY, KM ^{[1
]}

BAUMLIN, Y ^{[1
]}

ANDRES, H ^{[1
]}

MANLEY, PW ^{[1
]}

机构：

[1] SANDOZ PHARMA LTD,DEPT DRUG DEV,CH-4002 BASEL,SWITZERLAND

来源：

JAPANESE JOURNAL OF PHARMACOLOGY | 1992年 / 58卷

关键词：

D O I：

暂无

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The K+ channel openers (KCOs) form a structurally heterogeneous group of compounds which relax smooth muscle by opening K+ channels in the plasmalemma. At present it is not known whether these drugs open the same K+channel in smooth muscle and, if so, whether they bind to the same site of this channel. To address these questions we present the first binding study with KCOs in a smooth muscle preparation.

引用

页码：P226 / P231

页数：6

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