SYPHILIS DIAGNOSIS - SCREENING BY ENZYME-IMMUNOASSAY AND VARIATION IN FLUORESCENT TREPONEMAL ANTIBODY ABSORBED (FTA-ABS) CONFIRMATORY TEST-PERFORMANCE

被引：0
作者：
CHRONAS, G [1 ]
MOYES, A [1 ]
YOUNG, H [1 ]
机构：
[1] UNIV EDINBURGH,SCH MED,STD DIAGNOST LAB,TEVIOT PL,EDINBURGH EH8 9AG,MIDLOTHIAN,SCOTLAND
来源：
MEDICAL LABORATORY SCIENCES | 1992年 / 49卷 / 01期
关键词：
ENZYME-LINKED IMMUNOSORBENT ASSAY; FLUORESCENT ANTIBODY TECHNIC; REAGENT KITS; DIAGNOSTIC; SYPHILIS;
D O I：
暂无
中图分类号：
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号：
1001 ;
摘要：
Four fluorescent treponemal antibody absorbed (FTA-ABS) test kits were evaluated with 86 treponemal and 84 non-treponemal sera selected with enzyme immunoassay (EIA). Agreement between all four kits was 63% for treponemal, and 50% for non-treponemal. sera. Discrepancies with treponemal sera were associated with low levels of antibody characterised by T. pallidum haemagglutination assay (TPHA) titres less-than-or-equal-to 160 and a negative Venereal Diseases Research Laboratory (VDRL) test. Discrepancies with non-treponemal sera were significantly associated with false reactivity on screening with EIA. Possible reasons for the differences obtained between kits, the importance of screening policies for pre-selecting sera, and the significance of equivocal (borderline) reactions on positive and negative predictive values are discussed.
引用
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页码：50 / 55
页数：6
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