DETERMINATION OF THE AGGLUTINATION REACTIONS USING POWER SPECTRAL-ANALYSIS OF THE DEPOLARIZED LIGHT-INTENSITY FLUCTUATIONS SCATTERED FROM MAGNETIC PARTICLES

被引:0
|
作者
NAMBA, A [1 ]
YAGINUMA, Y [1 ]
MUSHA, T [1 ]
机构
[1] TOKYO INST TECHNOL,DEPT APPL ELECTR,MIDORI KU,YOKOHAMA,KANAGAWA 227,JAPAN
来源
JAPANESE JOURNAL OF APPLIED PHYSICS PART 1-REGULAR PAPERS SHORT NOTES & REVIEW PAPERS | 1991年 / 30卷 / 08期
关键词
MAGNETIC PARTICLE; LIGHT SCATTERING; DEPOLARIZATION; AGGLUTINATION; POWER SPECTRAL ANALYSIS; FLUCTUATION;
D O I
10.1143/JJAP.30.1901
中图分类号
O59 [应用物理学];
学科分类号
摘要
Presented here is a new optical method for evaluating the agglutination reactions of magnetic particles. Light intensity fluctuations scattered from the particles are detected by a cross-polarized optical measurement system. As soon as the electrolyte (NaCl)-induced coagulation of 2 min in a uniform magnetic field is completed, the sample data are gathered under the influence of a half-wave rectified magnetic field. The power spectral density has a strong peak at the frequency of the applied magnetic field. The spectral peak significantly increases by more than 10(3) with the NaCl concentration in the range between 0.03 and 0.1 mol/l. Furthermore, a sensitive immunoassay by means of magnetic particles can be achieved in a short-time measurement without any complex procedures.
引用
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页码:1901 / 1905
页数:5
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