INTERACTION OF CALCIUM-IONS WITH GLYCOCHOLATE MICELLES IN AQUEOUS-SOLUTION

被引：53

作者：

WILLIAMSON, BWA ^{[1
]}

PERCYROBB, IW ^{[1
]}

机构：

[1] UNIV EDINBURGH, ROYAL INFIRM, DEPT CLIN CHEM, EDINBURGH EH3 9YW, MIDLOTHIAN, SCOTLAND

来源：

BIOCHEMICAL JOURNAL | 1979年 / 181卷 / 01期

关键词：

D O I：

10.1042/bj1810061

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The formation of soluble complexes of Ca2+ ions and glycocholate has been demonstrated. The dissociation constant is 26 nmol/litre and a maximum of 2 Ca2+ ions are bound to each glycocholate micelle. The formation of this complex is shown to be reversible. Binding is increased by the introduction of phosphatidylcholine into the micelle; it is decreased by a decrease in pH and by increased counter-ion concentration. The biological significance of these effects is discussed.

引用

页码：61 / 66

页数：6

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