2ND MESSENGERS OF INSULIN ACTION

被引：3
|
作者：
SALTIEL, AR
机构：
[1] Rockefeller University, New York
来源：
TRENDS IN ENDOCRINOLOGY AND METABOLISM | 1990年 / 1卷 / 03期
关键词：
D O I：
10.1016/1043-2760(90)90029-3
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The molecular events involved in coupling the insulin receptor to the regulation of cellular metabolism remain unknown. Recent studies indicate that some of insulin's actions may be mediated by a novel oligosaccharide. This molecule is generated in cells by the insulin-dependent hydrolysis of a novel membrane glycolipid, termed a glycosyl-phosphatidylinositol. This glycolipid is structurally similar to a newly described protein anchor. The evaluation of the hormonal regulation of this new glycolipid may yield information on a new mechanism of signal transduction. © 1990.
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页码：158 / 163
页数：6
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