ACUTE MONOCYTIC LEUKEMIA IN A DOG WITH X-LINKED SEVERE COMBINED IMMUNODEFICIENCY

被引：4

作者：

FELSBURG, PJ ^{[1
]}

SOMBERG, RL ^{[1
]}

KRAKOWKA, GS ^{[1
]}

机构：

[1] OHIO STATE UNIV, COLL VET MED, DEPT VET PATHOBIOL, COLUMBUS, OH 43210 USA

来源：

CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY | 1994年 / 1卷 / 04期

关键词：

D O I：

10.1128/CDLI.1.4.379-384.1994

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We describe the occurrence of acute monocytic leukemia in a dog with X-linked severe combined immunodeficiency (XSCID) that had been raised in a gnotobiotic environment for 20 months. This case represents the first reported instance of malignancy in canine XSCID, the first case of acute monocytic leukemia in any species with severe combined immunodeficiency, and the first documented malignancy in any species with XSCID that was not associated with immunotherapy.

引用

页码：379 / 384

页数：6

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