THE RELATIONSHIP BETWEEN BODY-COMPOSITION AND PLASMA-CONCENTRATIONS OF EXOGENOUSLY ADMINISTERED URINARY FOLLICLE-STIMULATING-HORMONE

被引：9
|
作者：
REMORGIDA, V
GIORDANO, M
LANERA, P
COSTANTINI, S
DECECCO, L
机构：
[1] Istituto di Ginecologia ed Ostetricia, Universitá di Genova, Ospedale San Martino, 16143 Genova, Viale Benedetto XV
来源：
HUMAN REPRODUCTION | 1993年 / 8卷 / 07期
关键词：
BODY COMPOSITION; MENOTROPHINS; OVULATION INDUCTION;
D O I：
10.1093/oxfordjournals.humrep.a138182
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
The aim of this study was to evaluate the plasma absorption of i.m. administered exogenous urinary follicle stimulating hormone (FSH) in relation to body fatness, leanness and cell mass. Body composition was measured by means of bioelectrical impedance. An immunoradiometric assay was used to assess the concentration of exogenous FSH in blood in patients with a pharmacologically induced hypogonadotrophism who were undergoing ovulation induction for assisted reproduction. No correlation was found between body composition and the hormone concentration in blood. According to our results, the different requirements of gonadotrophin administration typically observed in patients of different weights are probably not related to different absorption and distribution of the drug.
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页码：1001 / 1004
页数：4
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