GENE-THERAPY - ADENOVIRUS VECTORS

被引：389
作者：
KOZARSKY, KF
WILSON, JM
机构：
[1] WISTAR INST ANAT & BIOL, INST HUMAN GENE THERAPY, PHILADELPHIA, PA 19104 USA
[2] UNIV PENN, PHILADELPHIA, PA 19104 USA
来源：
CURRENT OPINION IN GENETICS & DEVELOPMENT | 1993年 / 3卷 / 03期
关键词：
D O I：
10.1016/0959-437X(93)90126-A
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
The past year has seen a proliferation in the use of recombinant, replication-defective adenoviruses for experimental models of gene therapy. The fact that adenovirus infects most cell types with no requirement for cell division, combined with the high titers and high efficiency of gene transfer obtainable with recombinant adenovirus, make it a promising system for in vivo human gene therapy.
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页码：499 / 503
页数：5
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