PRIMARY HYPERPARATHYROIDISM OR HYPERCALCEMIA OF MALIGNANCY

被引：13

作者：

BIRKELAND, KI ^{[1
]}

GALLEFOSS, F ^{[1
]}

OLSSON, S ^{[1
]}

HAUG, E ^{[1
]}

机构：

[1] CENT HOSP VEST AGDER,DEPT INTERNAL MED,KRISTIANSAND,NORWAY

来源：

SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION | 1992年 / 52卷 / 04期

关键词：

INTACT PARATHYROID HORMONE (PTH) AND PTH-RELATED PEPTIDE (PTH-RP);

D O I：

10.3109/00365519209088368

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

The introduction ot two-site immunometric assays measuring intact parathyroid hormone (PTH) and radioimmunoassays measuring PTH-related peptide (PTH-RP) have simplified the evaluation of patients with hypercalcaemia. We present a 63-year-old man with recurrent hypercalcaemia after surgical treatment for primary hyperparathyroidism 3 years previously. PTH measured with a mid-region radioimmunoassay gave normal values, at the same level as during his primary hyperparathyroidism. Intact PTH was, however, clearly suppressed, and he had a highly elevated level of PTH-RP. This suggested that he had humoral hypercalcaemia of malignancy. The patient died after 2 months, and at autopsy an adenocarcinoma of the pancreas with no skeletal metastases was found.

引用

页码：347 / 349

页数：3