STRUCTURE-ACTIVITY-RELATIONSHIPS OF THE SAPONINS DIOSCIN AND DIOSCININ

被引：41
|
作者：
TAKECHI, M [1 ]
SHIMADA, S [1 ]
TANAKA, Y [1 ]
机构：
[1] SHIMADA PHARMACEUT INST,SUMINOE KU,OSAKA 559,JAPAN
来源：
PHYTOCHEMISTRY | 1991年 / 30卷 / 12期
关键词：
STRUCTURE ACTIVITY RELATIONSHIPS; HEMOLYSIS; ANTIFUNGAL ACTIVITY; DIOSCIN; DIOSCININ; SAPONINS;
D O I：
10.1016/0031-9422(91)83441-M
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Hemolytic and antifungal activities of partial acid hydrolysates of dioscin and dioscinin were compared. In general, these activities were proportional to the number of sugar residues and those derivatives having branched sugar chains showed higher activities than those with straight chains. The 17-hydroxyl group of the dioscinin derivatives reduced both biological activities.
引用
收藏
页码：3943 / 3944
页数：2
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