EFFECT OF CHLORPROMAZINE HYDROCHLORIDE ON THE FORMATION OF MICRONUCLEI IN THE BONE-MARROW OF MICE EXPOSED TO GAMMA-RADIATION

被引：0
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作者：
JAGETIA, GC
机构：
来源：
HEREDITAS | 1991年 / 115卷 / 03期
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暂无
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
The frequency of micronuclei was determined in the bone marrow of female BALB/c mice treated with various doses of chlorpromazine hydrochloride (CPZ) before exposure to 4.0 Gy of gamma radiation at 24 h post-exposure. In animals treated with CPZ alone, the frequency of micronuclei increased with the increase in drug dose. A similar pattern was observed when the mice were exposed to 4.0 Gy radiation after CPZ treatment. The dose response curves thus obtained for the CPZ treated and CPZ+ irradiated groups were linear quadratic.
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页码：195 / 199
页数：5
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