C-ACYLATION UNDER VIRTUALLY NEUTRAL CONDITIONS

被引：332
作者：
BROOKS, DW [1 ]
LU, LDL [1 ]
MASAMUNE, S [1 ]
机构：
[1] UNIV ALBERTA,DEPT CHEM,EDMONTON T6G 2G2,ALBERTA,CANADA
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH | 1979年 / 18卷 / 01期
关键词：
D O I：
10.1002/anie.197900722
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Acylations is syntheses of natural products often have to be performed under very mild conditions. The neutral Mg salt of a malonic thiol half‐ester of type 1 permits acylation of imidazolides (Im=1‐imidazolyl) in practically neutral solution. Numerous acid‐ and base‐labile groups survive this treatment. (Figure Presented.) Copyright © 1979 by Verlag Chemie, GmbH, Germany
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页码：72 / 74
页数：3
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