MONOCLONAL-ANTIBODY AGAINST THE PLATELET GLYCOPROTEIN (GP) IIB/IIIA RECEPTOR PREVENTS CORONARY-ARTERY REOCCLUSION AFTER REPERFUSION WITH RECOMBINANT TISSUE-TYPE PLASMINOGEN-ACTIVATOR IN DOGS

被引：241
作者：
YASUDA, T
GOLD, HK
FALLON, JT
LEINBACH, RC
GUERRERO, JL
SCUDDER, LE
KANKE, M
SHEALY, D
ROSS, MJ
COLLEN, D
COLLER, BS
机构：
[1] MASSACHUSETTS GEN HOSP,DIV CARDIAC,CARDIAC UNIT,ACC3A,SUITE 380,BOSTON,MA 02114
[2] MASSACHUSETTS GEN HOSP,DEPT MED,BOSTON,MA 02114
[3] MASSACHUSETTS GEN HOSP,DEPT PATHOL,BOSTON,MA 02114
[4] HARVARD UNIV,SCH MED,BOSTON,MA 02115
[5] SUNY STONY BROOK,DIV HEMATOL,STONY BROOK,NY 11794
[6] UNIV VERMONT,COLL MED,DEPT BIOCHEM,BURLINGTON,VT 05402
[7] UNIV VERMONT,COLL MED,DEPT MED,BURLINGTON,VT 05402
[8] CENTOCOR INC,MALVERN,PA 19355
[9] GENENTECH INC,S SAN FRANCISCO,CA 94080
来源：
JOURNAL OF CLINICAL INVESTIGATION | 1988年 / 81卷 / 04期
关键词：
D O I：
10.1172/JCI113446
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
引用
收藏
页码：1284 / 1291
页数：8
相关论文
共 25 条
[1]  
AIKEN JW, 1981, J PHARMACOL EXP THER, V219, P299
[2]   REACTIVITY OF A MONOCLONAL-ANTIBODY WITH HUMAN OVARIAN-CARCINOMA [J].
BAST, RC ;
FEENEY, M ;
LAZARUS, H ;
NADLER, LM ;
COLVIN, RB ;
KNAPP, RC .
JOURNAL OF CLINICAL INVESTIGATION, 1981, 68 (05) :1331-1337
[3]   CORONARY THROMBOLYSIS WITH RECOMBINANT HUMAN TISSUE-TYPE PLASMINOGEN-ACTIVATOR - A PROSPECTIVE, RANDOMIZED, PLACEBO-CONTROLLED TRIAL [J].
COLLEN, D ;
TOPOL, EJ ;
TIEFENBRUNN, AJ ;
GOLD, HK ;
WEISFELDT, ML ;
SOBEL, BE ;
LEINBACH, RC ;
BRINKER, JA ;
LUDBROOK, PA ;
YASUDA, I ;
BULKLEY, BH ;
ROBISON, AK ;
HUTTER, AM ;
BELL, WR ;
SPADARO, JJ ;
KHAW, BA ;
GROSSBARD, EB .
CIRCULATION, 1984, 70 (06) :1012-1017
[4]  
COLLER BS, 1986, BLOOD, V68, P783
[5]   A NEW MURINE MONOCLONAL-ANTIBODY REPORTS AN ACTIVATION-DEPENDENT CHANGE IN THE CONFORMATION AND OR MICROENVIRONMENT OF THE PLATELET GLYCOPROTEIN IIB/IIIA COMPLEX [J].
COLLER, BS .
JOURNAL OF CLINICAL INVESTIGATION, 1985, 76 (01) :101-108
[6]   A MURINE MONOCLONAL-ANTIBODY THAT COMPLETELY BLOCKS THE BINDING OF FIBRINOGEN TO PLATELETS PRODUCES A THROMBASTHENIC-LIKE STATE IN NORMAL PLATELETS AND BINDS TO GLYCOPROTEINS-IIB AND OR GLYCOPROTEIN-IIIA [J].
COLLER, BS ;
PEERSCHKE, EI ;
SCUDDER, LE ;
SULLIVAN, CA .
JOURNAL OF CLINICAL INVESTIGATION, 1983, 72 (01) :325-338
[7]  
COLLER BS, 1986, IN PRESS ANN NY ACAD
[8]  
COLLER BS, 1986, BLOOD, V66, P1456
[9]  
CONRAD J, 1980, THROMB RES, V20, P143
[10]  
DAVIES MJ, 1985, BRIT HEART J, V53, P363
123