Depression in dementia

被引：55
作者：
Kitching, David [1 ]
机构：
[1] Concord Hosp, Sydney, NSW, Australia
来源：
AUSTRALIAN PRESCRIBER | 2015年 / 38卷 / 06期
关键词：
Alzheimer's disease; antidepressants; dementia; depression;
D O I：
10.18773/austprescr.2015.071
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
People with dementia of any type have a high incidence of major depression. The occurrence of a first major depressive episode in an older adult is a risk factor for developing dementia. Management of depression in a person with dementia should be enthusiastic with an aim to optimise quality of life. Non-pharmacological and pharmacological strategies are both important in treating depression in dementia and management of these patients requires a collaborative approach. Selective serotonin reuptake inhibitors are the first-line pharmacotherapy for depression in dementia, although they are less likely to be effective in older people.
引用
收藏
页码：209 / 211
页数：3
相关论文
共 19 条
[1]   CORNELL SCALE FOR DEPRESSION IN DEMENTIA [J].
ALEXOPOULOS, GS ;
ABRAMS, RC ;
YOUNG, RC ;
SHAMOIAN, CA .
BIOLOGICAL PSYCHIATRY, 1988, 23 (03) :271-284
[2]   Sertraline or mirtazapine for depression in dementia (HTA-SADD): a randomised, multicentre, double-blind, placebo-controlled trial [J].
Banerjee, Sube ;
Hellier, Jennifer ;
Dewey, Michael ;
Romeo, Renee ;
Ballard, Clive ;
Baldwin, Robert ;
Bentham, Peter ;
Fox, Chris ;
Holmes, Clive ;
Katona, Cornelius ;
Knapp, Martin ;
Lawton, Claire ;
Lindesay, James ;
Livingston, Gill ;
McCrae, Niall ;
Moniz-Cook, Esme ;
Murray, Joanna ;
Nurock, Shirley ;
Orrell, Martin ;
O'Brien, John ;
Poppe, Michaela ;
Thomas, Alan ;
Walwyn, Rebecca ;
Wilson, Kenneth ;
Burns, Alistair .
LANCET, 2011, 378 (9789) :403-411
[3]   Depression Predicts Cognitive Disorders in Older Primary Care Patients [J].
Boyle, Lisa L. ;
Porsteinsson, Anton P. ;
Cui, Xingjia ;
King, Deborah A. ;
Lyness, Jeffrey M. .
JOURNAL OF CLINICAL PSYCHIATRY, 2010, 71 (01) :74-79
[4]   Depression in dementia: epidemiology, mechanisms, and treatment [J].
Enache, Daniela ;
Winblad, Bengt ;
Aarsland, Dag .
CURRENT OPINION IN PSYCHIATRY, 2011, 24 (06) :461-472
[5]   Depression in Alzheimer's disease: specificity of depressive symptoms using three different clinical criteria [J].
Engedal, Knut ;
Barca, Maria Lage ;
Laks, Jerson ;
Selbaek, Geir .
INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY, 2011, 26 (09) :944-951
[6]   Efficacy and Cognitive Side Effects of Electroconvulsive Therapy (ECT) in Depressed Elderly Inpatients With Coexisting Mild Cognitive Impairment or Dementia [J].
Hausner, Lucrezia ;
Damian, Marinella ;
Sartorius, Alexander ;
Froelich, Lutz .
JOURNAL OF CLINICAL PSYCHIATRY, 2011, 72 (01) :91-97
[7]   The geriatric depression scale and the Cornell Scale for Depression in Dementia. A validity study [J].
Korner, Alex ;
Lauritzen, Lise ;
Abelskov, Kirsten ;
Gulmann, Nils ;
Brodersen, Anne Marie ;
Wedervang-Jensen, Torben ;
Kjeldgaard, Karen Marie .
NORDIC JOURNAL OF PSYCHIATRY, 2006, 60 (05) :360-364
[8]   The Montgomery-Asberg Depression Rating Scale and the Cornell Scale for Depression in Dementia: A Validation Study With Patients Exhibiting Early-Onset Dementia [J].
Leontjevas, Ruslan ;
van Hooren, Susan ;
Mulders, Ans .
AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY, 2009, 17 (01) :56-64
[9]   NEW DEPRESSION SCALE DESIGNED TO BE SENSITIVE TO CHANGE [J].
MONTGOMERY, SA ;
ASBERG, M .
BRITISH JOURNAL OF PSYCHIATRY, 1979, 134 (APR) :382-389
[10]   A Systematic Review and Meta-Analysis of Placebo-Controlled Antidepressant Studies in People with Depression and Dementia [J].
Nelson, J. Craig ;
Devanand, Davangere P. .
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2011, 59 (04) :577-585
12