Isolation and some properties of ciguatoxin

被引：62

作者：

Legrand, A. M. ^{[1
]}

Litaudon, M. ^{[1
]}

Genthon, J. N. ^{[1
]}

Bagnis, R. ^{[1
]}

Yasumoto, T. ^{[2
]}

机构：

[1] Inst Terr Recherches Med Louis Malarde, Papeete, Tahiti, France

[2] Tohoku Univ, Fac Agr, Dept Food Chem, Sendai, Miyagi 981, Japan

来源：

JOURNAL OF APPLIED PHYCOLOGY | 1989年 / 1卷 / 02期

关键词：

ciguatoxin; ciguatera; Gambierdiscus toxicus; moray eel; purification; H-1; NMR;

D O I：

10.1007/BF00003882

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Ciguatoxin, the principal toxin of ciguatera produced by a toxic dinoflagellate and accumulated through the food chain in the viscera of moray eels, was purified. The probable molecular formula C60H86O19 was obtained for the first time by high resolution mass spectrometry. H-1 NMR spectra suggested the presence of a primary hydroxyl group suitable for preparing an antigen necessary to develop an enzyme immunoassay.

引用

页码：183 / 188

页数：6

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