Oligopeptide Sequence Analysis by Collision-activated Dissociation of Multiply Charged Ions

被引:48
作者
Hunt, Donald F. [1 ]
Zhu, Nian-Zhou [1 ]
Shabanowitz, Jeffrey [1 ]
机构
[1] Univ Virginia, Dept Chem, Charlottesville, VA 22901 USA
基金
美国国家卫生研究院;
关键词
D O I
10.1002/rcm.1290030408
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Collision-activated dissociation of an [M + 2H](2+) ion from a tryptic peptide of molecular weight 2315.3 provides sets of overlapping fragments that allow the amino acid sequence of this peptide to be determined on a triple quadrupole mass spectrometer having a mass range of 1800 Da.
引用
收藏
页码:122 / 124
页数:4
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