CALCEIN - A NEW DYE FOR EVALUATION OF THE BLOOD-RETINAL BARRIER BY FLUOROPHOTOMETRY

被引：0
|
作者：
GOLSHANI, MR [1 ]
KHOOBEHI, B [1 ]
PEYMAN, GA [1 ]
机构：
[1] LOUISIANA STATE UNIV,MED CTR,SCH MED,CTR EYE,NEW ORLEANS,LA 70112
来源：
INTERNATIONAL OPHTHALMOLOGY | 1993年 / 17卷 / 06期
关键词：
BLOOD-RETINAL BARRIER; CALCEIN; CARBOXYFLUORESCEIN; FLUOROPHOTOMETRY; SODIUM FLUORESCEIN;
D O I：
暂无
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
A vitreous fluorophotometry study was performed on rabbits to compare the characteristics of carboxyfluorescein and calcein with those of sodium fluorescein. Our results demonstrated that carboxyfluorescein and calcein attained midvitreous concentrations similar in magnitude to fluorescein approximately one hour after injection of the dye. As long as three to four hours after injection of the dye, the mean fluorescence levels of calcein in the chorioretina were much higher than those of sodium fluorescein and carboxyfluorescein. These results point out that calcein has potential experimental and clinical use as a probe of the blood-ocular barrier as well as in experimental and clinical angiography of the fundus.
引用
收藏
页码：349 / 353
页数：5
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