ISOLATION OF AN ACTIVATOR FOR PROSTAGLANDIN HYDROPEROXIDASE FROM BOVINE VESICULAR GLAND CYTOSOL AND ITS IDENTIFICATION AS URIC-ACID

被引：45
作者：
OGINO, N
YAMAMOTO, S
HAYAISHI, O
TOKUYAMA, T
机构：
[1] KYOTO UNIV,FAC MED,DEPT MED CHEM,SAKYO KU,KYOTO 606,JAPAN
[2] OSAKA CITY UNIV,FAC SCI,DEPT CHEM,OSAKA 558,JAPAN
来源：
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1979年 / 87卷 / 01期
关键词：
D O I：
10.1016/0006-291X(79)91664-4
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The enzymatic conversion of prostaglandin G1 to H1 was stimulated by an activator present in the cytosol of bovine vesicular gland. The activator was purified by Sephadex G-25 gel filtration and Dowex 1 column chromatography. The purified activator was identified to be uric acid by thin layer chromatography, ultraviolet and infrared absorption spectroscopy and combined gas chromatography-mass spectroscopy. Among various purine compounds tested, only uric acid and 2,8-dihydroxyadenine were active. © 1979.
引用
收藏
页码：184 / 191
页数：8
相关论文
共 50 条
  • [31] STUDIES ON HORMONES FROM ANTERIOR PITUITARY GLAND .I. IDENTIFICATION AND ISOLATION OF GROWTH HORMONE AND PROLACTIN FROM GRANULAR FRACTION OF BOVINE PITUITARY
    KWA, HG
    VANDERBE.EM
    FELTKAMP, CA
    RUMKE, P
    BLOEMEND.H
    BIOCHIMICA ET BIOPHYSICA ACTA, 1965, 111 (02) : 447 - &
  • [32] Isolation and identification of dihydroartemisinic acid from Artemisia annua and its possible role in the biosynthesis of artemisinin
    Wallaart, TE
    van Uden, W
    Lubberink, HGM
    Woerdenbag, HJ
    Pras, N
    Quax, WJ
    JOURNAL OF NATURAL PRODUCTS, 1999, 62 (03): : 430 - 433
  • [33] Isolation and Identification of Ellagic Acid from Rosa roxburghii Tratt and Its Optimization of Extraction Process
    Liu Y.
    Ji J.
    Zhang S.
    Tang L.
    Chen L.
    Zhang M.
    Wang P.
    Li T.
    Gao X.
    Science and Technology of Food Industry, 2023, 44 (08) : 212 - 220
  • [34] Isolation and identification of an acid-tolerant Lactobacillus species from chicken intestine and its application
    Wang, Mingcheng
    Tang, Jiaze
    Wang, Gailing
    Guo, Yanan
    Guo, Lei
    Li, Enzhong
    Journal of Biotech Research, 2022, 13 : 142 - 151
  • [35] SERUM URIC-ACID AND ITS RELATION TO CARDIOVASCULAR RISK-FACTORS IN CHILDREN AND YOUNG-ADULTS FROM A BIRACIAL COMMUNITY - BOGALUSA HEART-STUDY
    AGAMAH, ES
    SRINIVASAN, SR
    WEBBER, LS
    BERENSON, GS
    CIRCULATION, 1990, 82 (04) : 228 - 228
  • [36] ISOLATION AND IDENTIFICATION OF γ-AMINOBU-TYRIC ACID AND QUANTITATIVE ANALYSIS OF ITS AMINO ACID CONTENTS FROM PANAX GINSENG
    杨柳
    叶蕴华
    袁洪生
    邢其毅
    Chinese Science Bulletin, 1991, (20) : 1706 - 1710
  • [37] STUDIES ON SECRETORY IMMUNOLOGLOBULIN-A (SIGA) AND ITS IMPORTANCE FOR DEFENCE MECHANISM OF BOVINE MAMMARY-GLAND AGAINST INFECTIONS .1. ISOLATION AND IDENTIFICATION OF IMMUNOGLOBULINS
    HUBLER, C
    HEESCHEN, W
    TOLLE, A
    HAMANN, J
    MILCHWISSENSCHAFT-MILK SCIENCE INTERNATIONAL, 1978, 33 (01): : 1 - 6
  • [38] 4,8,12-TRIMETHYLTRIDECANOIC ACID - ITS ISOLATION AND IDENTIFICATION FROM SHEEP PERINEPHRIC FAT
    HANSEN, RP
    BIOCHIMICA ET BIOPHYSICA ACTA, 1968, 164 (03) : 550 - &
  • [39] ISOLATION AND IDENTIFICATION OF VASOPRESSIN-IMMUNOREACTIVE AND OXYTOCIN-IMMUNOREACTIVE SUBSTANCES FROM BOVINE PINEAL-GLAND - PRESENCE OF N-ALPHA-ACETYLOXYTOCIN
    LIU, B
    POULTER, L
    NEACSU, C
    BURBACH, JPH
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1988, 263 (01) : 72 - 75
  • [40] SERUM URIC-ACID AND ITS RELATION TO CARDIOVASCULAR-DISEASE RISK-FACTORS IN CHILDREN AND YOUNG-ADULTS FROM A BIRACIAL COMMUNITY - THE BOGALUSA HEART-STUDY
    AGAMAH, ES
    SRINIVASAN, SR
    WEBBER, LS
    BERENSON, GS
    JOURNAL OF LABORATORY AND CLINICAL MEDICINE, 1991, 118 (03): : 241 - 249
12345