NUCLEAR-PORES IN THE APOPTOTIC CELL

被引：55
|
作者：
FALCIERI, E
GOBBI, P
CATALDI, A
ZAMAI, L
FAENZA, I
VITALE, M
机构：
[1] CNR, IST CODIVILLA PUTTI, IST CITOMORFOL NORMALE & PATOL, I-40126 BOLOGNA, ITALY
[2] UNIV BOLOGNA, IST ANAT UMANA NORMALE, I-40126 BOLOGNA, ITALY
[3] IST ORTOPED RIZZOLI, BIOL CELL MICROSC ELETTR LAB, BOLOGNA, ITALY
[4] UNIV BRESCIA, DIPARTIMENTO SCI BIOMED & BIOTECHNOL, SEZ ANAT UMANA, BRESCIA, ITALY
来源：
HISTOCHEMICAL JOURNAL | 1994年 / 26卷 / 09期
关键词：
D O I：
10.1007/BF00158206
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
During apoptosis, nuclear pores undergo strong modifications, which are described here in five different apoptotic models. Conventional electron microscopy, supported by freeze-fracture analysis, showed a constant migration of nuclear pores towards the diffuse chromatin areas. In contrast, dense chromatin areas appear pore-free and are frequently surrounded by strongly dilated cistemae. A possible functional significance of this pore behaviour during apoptosis is discussed.
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页码：754 / 763
页数：10
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