ENANTIOSELECTIVE AND STEREOSELECTIVE ROUTE TO THE TAXOL SIDE-CHAIN VIA ASYMMETRIC EPOXIDATION OF TRANS-CINNAMYL ALCOHOL AND SUBSEQUENT EPOXIDE RING-OPENING

被引：32

作者：

BONINI, C ^{[1
]}

RIGHI, G ^{[1
]}

机构：

[1] UNIV ROMA LA SAPIENZA,DIPARTIMENTO CHIM,CNR,CTR STUDIO CHIM SOSTANZE ORGAN NAT,I-00185 ROME,ITALY

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1994年 / 24期

关键词：

D O I：

10.1039/c39940002767

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The first route to the side chain of Taxol and Taxotere, employing asymmetric epoxidation (AE) of trans-cinnamyl alcohol and a new highly regio- and stereo-selective opening of the epoxide ring with MgBr2, is described.

引用

页码：2767 / 2768

页数：2

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