ENANTIOSELECTIVE AND STEREOSELECTIVE ROUTE TO THE TAXOL SIDE-CHAIN VIA ASYMMETRIC EPOXIDATION OF TRANS-CINNAMYL ALCOHOL AND SUBSEQUENT EPOXIDE RING-OPENING

被引：32
作者：
BONINI, C [1 ]
RIGHI, G [1 ]
机构：
[1] UNIV ROMA LA SAPIENZA,DIPARTIMENTO CHIM,CNR,CTR STUDIO CHIM SOSTANZE ORGAN NAT,I-00185 ROME,ITALY
来源：
JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1994年 / 24期
关键词：
D O I：
10.1039/c39940002767
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The first route to the side chain of Taxol and Taxotere, employing asymmetric epoxidation (AE) of trans-cinnamyl alcohol and a new highly regio- and stereo-selective opening of the epoxide ring with MgBr2, is described.
引用
收藏
页码：2767 / 2768
页数：2
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