CONCURRENT ACUTE MYELOID-LEUKEMIA AND SYSTEMIC MASTOCYTOSIS

被引：33
作者：
WONG, KF
CHAN, JKC
CHAN, JCW
KWONG, YL
MA, SK
CHOW, TC
机构：
[1] QUEEN ELIZABETH HOSP,MED UNIT C,KOWLOON,HONG KONG
[2] QUEEN MARY HOSP,DEPT PATHOL,HEMATOL SECT,HONG KONG,HONG KONG
来源：
AMERICAN JOURNAL OF HEMATOLOGY | 1991年 / 38卷 / 03期
关键词：
MASTOCYTOSIS; ACUTE LEUKEMIA; CHEMOTHERAPY;
D O I：
10.1002/ajh.2830380319
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
A 51-year-old woman presented with concurrent systemic mastocytosis and acute myeloid leukemia associated with a clonal karyotypic anomaly of t(8;21). Cytochemical, histologic, and cytogenetic studies helped in the distinction from a recently described entity: acute myeloid leukemia with marrow basophilia. Although the leukemia responded well to aggressive chemotherapy, the mastocytosis component worsened, illustrating the inherent resistance of mastocytosis to chemotherapy.
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页码：243 / 244
页数：2
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