共 50 条
- [32] Design, synthesis, and biological evaluation of 2,4-diamino-5-methyl-6-substituted-pyrrolo[2,3-d]pyrimidines as dihydrofolate reductase inhibitorsJOURNAL OF MEDICINAL CHEMISTRY, 2004, 47 (14) : 3689 - 3692Gangjee, ALin, XQueener, SF
- [33] Synthesis and biological activity of 5-desmethyl-2,4-diaminopyrido[2,3-d]pyrimidine dihydrofolate reductase inhibitors.ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1997, 213 : 245 - MEDIGangjee, AAdair, OQueener, SF
- [34] SYNTHESIS OF 2-C-14-2, 4-DIAMINO-5-ADAMANTYL-6-METHYL PYRIMIDINE (DAMP) AND ITS DISTRIBUTION IN RAT TISSUESFEDERATION PROCEEDINGS, 1975, 34 (03) : 734 - 734ZAKRZEWSKI, SFDAVE, CVMEAD, LH
- [35] 2,4-DIAMINOTHIENO[2,3-D]PYRIMIDINE ANALOGS OF TRIMETREXATE AND PIRITREXIM AS POTENTIAL INHIBITORS OF PNEUMOCYSTIS-CARINII AND TOXOPLASMA-GONDII DIHYDROFOLATE-REDUCTASEJOURNAL OF MEDICINAL CHEMISTRY, 1993, 36 (21) : 3103 - 3112ROSOWSKY, AMOTA, CEWRIGHT, JEFREISHEIM, JHHEUSNER, JJMCCORMACK, JJQUEENER, SF
- [36] BIOCHEMICAL AND CHEMOTHERAPEUTIC STUDIES ON 2,4-DIAMINO-6-(2,5-DIMETHOXYBENZYL)-5-METHYLPYRIDO[2,3-D]PYRIMIDINE (BW 301U), A NOVEL LIPID-SOLUBLE INHIBITOR OF DIHYDROFOLATE-REDUCTASECANCER RESEARCH, 1982, 42 (10) : 3987 - 3994DUCH, DSEDELSTEIN, MPBOWERS, SWNICHOL, CA
- [37] 2,4-Diamino-6-substituted pyrido[3,2-d]pyrimidine inhibitors of Pneumocystis carinii and Toxoplasma gondii dihydrofolate reductases.ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1996, 212 : 38 - MEDIGangjee, AZhu, YMQueener, SF
- [38] IRREVERSIBLE ENZYME INHIBITORS .166. ACTIVE-SITE-DIRECTED IRREVERSIBLE INHIBITORS OF DIHYDROFOLIC REDUCTASE DERIVED FROM 2,4-DIAMINO-5-(3,4-DICHLOROPHENYL)PYRIMIDINE WITH 6 SUBSTITUENTS AND SOME FACTORS IN THEIR CELL WALL TRANSPORTJOURNAL OF MEDICINAL CHEMISTRY, 1970, 13 (01) : 82 - &BAKER, BRVERMEULE.NM
- [39] INHIBITION OF TUMOR GROWTH BY 2,4 DIAMINO-5 (1-ADAMANTYL)-6-METHYLPYRIMIDINE (DAMP), A NEW ANTIFOLIC AGENTPROCEEDINGS OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH, 1972, 13 (MAR): : 70 - &ZAKRZEWS.SFROSEN, F
- [40] IRREVERSIBLE ENZYME INHIBITORS . 137 . ACTIVE-SITE-DIRECTED IRREVERSIBLE INHIBITORS OF DIHYDROFOLIC REDUCTASE DERIVED FROM 6-(P-AMINOMETHYLPHENOXYMETHYL)-2,4-DIAMINO-5-(3,4-DICHLOROPHENYL)PYRIMIDINE BEARING A TERMINAL SULFONYL FLUORIDEJOURNAL OF MEDICINAL CHEMISTRY, 1969, 12 (01) : 86 - +BAKER, BRVERMEULEN, NM