STRUCTURAL COMPARISON OF 2,4-DIAMINO-5-(1-ADAMANTYL)-6-METHYL PYRIMIDINE ETHYLSULFONATE WITH OTHER PYRIMIDINE INHIBITORS OF DIHYDROFOLATE-REDUCTASE

被引：0

作者：

CODY, V

ZAKRZEWSKI, SF

机构：

[1] MED FDN BUFFALO,BUFFALO,NY 14203

[2] NEW YORK STATE DEPT HLTH,ROSWELL PK MEM INST,BUFFALO,NY 14263

来源：

FEDERATION PROCEEDINGS | 1980年 / 39卷 / 06期

关键词：

D O I：

暂无

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：1856 / 1856

页数：1

共 50 条

[21] 2,4-diamino-6,7-dihydro-5H-cyclopenta[d]pyrimidine analogues of trimethoprim as inhibitors of Pneumocystis carinii and Toxoplasma gondii dihydrofolate reductase [J].

Rosowsky, A ;

Papoulis, AT ;

Queener, SF .

JOURNAL OF MEDICINAL CHEMISTRY, 1998, 41 (06) :913-918

[22] PRECLINICAL EVALUATION OF BW301U,2,4-DIAMINO-6-(2,5-DIMETHOXYBENZYL)-5-METHYLPYRIDO-[2,3D]PYRIMIDINE, A LIPOPHILIC INHIBITOR OF DIHYDROFOLATE-REDUCTASE [J].

SIGEL, CW ;

BLUM, MR ;

WOOLLEY, JL ;

FOSS, RG ;

LIAO, SHT ;

EVERITT, BJ ;

MACKLIN, AW ;

NICHOL, CA .

PROCEEDINGS OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH, 1984, 25 (MAR) :310-310

[23] Synthesis of (2,4-Diamino-5-(3′,4′,5′-trimethoxybenzyl) Pyrimidine) Copper (II) Complex at 20–25 °C and its Structural Characterization [J].

Uzma Habib ;

Amin Badshah ;

Ulrich Flörke ;

Rizwana Aleem Qureshi ;

Bushra Mirza ;

Azeem Nazar-ul-Islam .

Journal of Chemical Crystallography, 2009, 39 :607-611

[24] 2,4-Diamino-5-deaza-6-substituted pyrido[2,3-d]pyrimidine antifolates as potent and selective nonclassical inhibitors of dihydrofolate reductases [J].

Gangjee, A ;

Vasudevan, A ;

Queener, SF ;

Kisliuk, RL .

JOURNAL OF MEDICINAL CHEMISTRY, 1996, 39 (07) :1438-1446

[25] 2,4-DIAMINOPYRIDO[3,2-D]PYRIMIDINE INHIBITORS OF DIHYDROFOLATE-REDUCTASE FROM PNEUMOCYSTIS-CARINII AND TOXOPLASMA-GONDII [J].

ROSOWSKY, A ;

FORSCH, RA ;

QUEENER, SF .

JOURNAL OF MEDICINAL CHEMISTRY, 1995, 38 (14) :2615-2620

[26] STRUCTURE OF 2,4-DIAMINO-5-(3,4,5-TRIMETHOXYBENZYL)PYRIMIDINE-5,5-DIETHYLBARBITURICACID (1-1) [J].

SHIMIZU, N ;

NISHIGAKI, S ;

NAKAI, Y ;

OSAKI, K .

ACTA CRYSTALLOGRAPHICA SECTION B-STRUCTURAL SCIENCE, 1982, 38 (AUG) :2309-2311

[27] CNDO/2 MOLECULAR-ORBITAL CONFORMATIONAL ENERGY STUDIES ON THE ANTI-NEOPLASTIC ANTI-FOLATE 2,4-DIAMINO-5-(1-ADAMANTYL)-6-ETHYLPYRIMIDINE [J].

WELSH, WJ ;

CODY, V .

FEDERATION PROCEEDINGS, 1983, 42 (04) :887-887

[28] Design, synthesis and biological evaluation of 2,4-diamino-6-methyl-5-substitutedpyrrolo[2,3-d]pyrimidines as dihydrofolate reductase inhibitors [J].

Gangjee, A ;

Jain, HD ;

Queener, SF .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 2005, 42 (04) :589-594

[29] Synthesis of (2,4-Diamino-5-(3′,4′,5′-trimethoxybenzyl) Pyrimidine) Copper (II) Complex at 20-25 °C and its Structural Characterization [J].

Habib, Uzma ;

Badshah, Amin ;

Floerke, Ulrich ;

Qureshi, Rizwana Aleem ;

Mirza, Bushra ;

Nazar-ul-Islam ;

Khan, Azeem .

JOURNAL OF CHEMICAL CRYSTALLOGRAPHY, 2009, 39 (08) :607-611

[30] Structural analysis of Pneumocystis carinii dihydrofolate reductase complexed with NADPH and 2,4-diamino-6-[2-(5-carboxypent-1-yn-1-yl)-5-methoxybenzyl]-5-methylpyrido[2,3-d]pyrimidine [J].

Cody, Vivian ;

Pace, Jim ;

Stewart, Elizabeth .

ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS, 2012, 68 :418-423

← 1 2 3 4 5 →