DIAGNOSTIC EVALUATION OF PATIENTS WITH HISTIOCYTOSIS-X

被引:21
作者
DIMENTBERG, RA [1 ]
BROWN, KLB [1 ]
机构
[1] MCGILL UNIV,MONTREAL CHILDRENS HOSP,DIV ORTHOPAED SURG,2300 TUPPER ST,ROOM C-1113,MONTREAL H3H 1P3,QUEBEC,CANADA
关键词
Diagnosis; Disseminated; Dysfunction; Localized; Progression; Histiocytosis X;
D O I
10.1097/01241398-199011000-00006
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
The natural history of histiocytosis X was reviewed in 52 patients to identify the characteristics of patients with localized versus disseminated disease. Two categories of patients were identified. Older patients with solitary or multiple bone lesions constituted a low-risk group. This group had a high rate of development of new bone lesions (55% were asymptomatic) but an excellent prognosis. Patients with soft tissue involvement constituted a group at high risk for disease progression and organ dysfunction. These patients required a more extensive diagnostic workup and systemic treatment. A diagnostic algorithm is proposed to identify these two groups. © 1990 Raven Press, Ltd., New York.
引用
收藏
页码:733 / 741
页数:9
相关论文
共 27 条
[1]  
Berry D.H., Gresik M.V., Humphrey G.B., Starling K., Vietti T., Boyett J., Marcus R., Natural history of histiocytosis X: A Pediatric Oncology Group study, Med Pediatr Oncol, 14, pp. 1-5, (1986)
[2]  
Bokkerink J., De Vaan G., Histiocytosis X, Eur J Pediatr, 135, pp. 129-146, (1980)
[3]  
Broadbent V., Pritchard J., Histiocytosis X—current controversies, Arch Dis Child, 60, pp. 605-607, (1985)
[4]  
Broadbent V., Davies E.G., Heaf D., Pincott J.R., Pritchard J., Levinsky R.J., Atherton D.J., Tucker S., Spontaneous remission of multisystem histiocytosis X, Lancet, 1, pp. 253-254, (1984)
[5]  
Capanna R., Springfield D.S., Ruggieri P., Biagini R., Picci P., Bacci G., Giunti A., Lorenzi E.G., Campanacci M., Direct cortisone injection in eosinophilic granuloma of bone: A preliminary report on 11 patients, J Pediatr Orthop, 5, pp. 339-342, (1985)
[6]  
Cassidy R.J., The current role of radiation therapy in the management of histiocytosis X, Hematol Oncol Clin North Am, 1, pp. 123-129, (1987)
[7]  
Cheyne C., Histiocytosis X, J Bone Joint Surg [Br], 53, pp. 366-382, (1971)
[8]  
Chu A., D'Angio G.J., Favara B.E., Ladish S., Nezelof C., Pritchard J., Report and recommendations of the Workshop on the Childhood Histiocytosis: Concepts and controversies, Med Pediatr Oncol, 14, pp. 104-117, (1986)
[9]  
Fowles J.V., Bobechko W.P., Solitary eosinophilic granuloma in bone, J Bone Joint Surg [Br], 52, pp. 238-243, (1970)
[10]  
Goldsmith D.P., Wimmer R.S., Histiocytosis syndromes, Musculoskeletal Diseases in Children, pp. 255-269, (1983)