INTEGRITY OF ESCHERICHIA-COLI P-PILI DURING BIOGENESIS - PROPERTIES AND ROLE OF PAPJ

被引：22

作者：

TENNENT, JM ^{[1
]}

LINDBERG, F ^{[1
]}

NORMARK, S ^{[1
]}

机构：

[1] UMEA UNIV,DEPT MICROBIOL,S-90187 UMEA,SWEDEN

来源：

MOLECULAR MICROBIOLOGY | 1990年 / 4卷 / 05期

关键词：

D O I：

10.1111/j.1365-2958.1990.tb00645.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The papJ gene of uropathogenic Escherichia coli is required to maintain the integrity of Galα(1‐4)Gal‐binding P pili. Electron microscopy and ELISA have established that strains carrying the papJ1 mutant allele have a large amount of pilus antigen free of the cells. In contrast to the whole pili released by strains unable to produce the PapH pilus anchor, the free papJ1 pili consist of variably sized segments that appear to result from Internal breakages to the pilus. The DNA sequence of papJ is presented and its gene product identified as an 18kD periplasmic protein that possesses homology with nucleotide‐binding proteins. PapJ may function as a ‘molecular chaperone’ directly or indirectly establishing the correct assembly of PapA subunits in the P pilus. Copyright © 1990, Wiley Blackwell. All rights reserved

引用

页码：747 / 758

页数：12

共 50 条

[1] IMMUNOCHEMICAL CHARACTERIZATION OF P-PILI FROM INVASIVE ESCHERICHIA-COLI
HANLEY, J
SALIT, IE
HOFMANN, T
INFECTION AND IMMUNITY, 1985, 49 (03) : 581 - 586
[2] Dynamic restacking of Escherichia coli P-pili
Lugmaier, Robert A.
Schedin, Staffan
Kuehner, Ferdinand
Benoit, Martin
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, 2008, 37 (02): : 111 - 120
[3] Dynamic restacking of Escherichia Coli P-pili
Robert A. Lugmaier
Staffan Schedin
Ferdinand Kühner
Martin Benoit
European Biophysics Journal, 2008, 37 : 111 - 120
[4] DISTRIBUTION OF TYPE-1 AND P-PILI ON UROPATHOGENIC ESCHERICHIA-COLI O6
GANDER, RM
THOMAS, VL
INFECTION AND IMMUNITY, 1987, 55 (02) : 293 - 297
[5] PRODUCTION AND CHARACTERIZATION OF MONOCLONAL-ANTIBODIES AGAINST PYELONEPHRITIS-ASSOCIATED P-PILI OF ESCHERICHIA-COLI
MIYATA, H
KATAOKA, S
MORIGUCHI, N
YAMAMOTO, T
MICHIBATA, I
KOBAYASHI, T
MAKI, S
PEDIATRIC NEPHROLOGY, 1994, 8 (03) : 270 - 274
[6] BIOGENESIS OF PILI ADHESINS ASSOCIATED WITH URINARY-TRACT INFECTIOUS ESCHERICHIA-COLI
NORMARK, S
HULTGREN, S
MARKLUND, BI
STROMBERG, N
TENNENT, J
ANTONIE VAN LEEUWENHOEK JOURNAL OF MICROBIOLOGY, 1988, 54 (05): : 405 - 409
[7] INVIVO EXPRESSION AND VARIATION OF ESCHERICHIA-COLI TYPE-1 AND P-PILI IN THE URINE OF ADULTS WITH ACUTE URINARY-TRACT INFECTIONS
KISIELIUS, PV
SCHWAN, WR
AMUNDSEN, SK
DUNCAN, JL
SCHAEFFER, AJ
INFECTION AND IMMUNITY, 1989, 57 (06) : 1656 - 1662
[8] ISOLATED ESCHERICHIA-COLI PILI ADHERE SPECIFICALLY TO THE INTESTINAL MUCOSAL SURFACE - EVIDENCE THAT PILI ARE AN ESCHERICHIA-COLI ADHERENCE FACTOR
BERENDSON, R
CHENEY, CP
BOEDEKER, EC
GASTROENTEROLOGY, 1980, 78 (05) : 1140 - 1140
[9] EFFECT OF PILI ON SUSCEPTIBILITY OF ESCHERICHIA-COLI TO PHAGOCYTOSIS
SILVERBLATT, FJ
DREYER, JS
SCHAUER, S
INFECTION AND IMMUNITY, 1979, 24 (01) : 218 - 223
[10] STRUCTURE OF COMMON PILI FROM ESCHERICHIA-COLI
MCMICHAEL, JC
OU, JT
JOURNAL OF BACTERIOLOGY, 1979, 138 (03) : 969 - 975

← 1 2 3 4 5 →