GENERALIZED RESISTANCE TO THYROID-HORMONE ASSOCIATED WITH A MUTATION IN THE LIGAND-BINDING DOMAIN OF THE HUMAN THYROID-HORMONE RECEPTOR-BETA

被引：251
作者：
SAKURAI, A
TAKEDA, K
AIN, K
CECCARELLI, P
NAKAI, A
SEINO, S
BELL, GI
REFETOFF, S
DEGROOT, LJ
机构：
[1] UNIV CHICAGO,THYROID STUDY UNIT,BOX 138,5841 S MARYLAND AVE,CHICAGO,IL 60637
[2] UNIV CHICAGO,DEPT MED,CHICAGO,IL 60637
[3] UNIV CHICAGO,DEPT PEDIAT,CHICAGO,IL 60637
[4] UNIV CHICAGO,DEPT BIOCHEM & MOLEC BIOL,CHICAGO,IL 60637
[5] UNIV CHICAGO,JOSEPH P KENNEDY JR MENTAL RETARDAT RES CTR,CHICAGO,IL 60637
[6] UNIV CHICAGO,HOWARD HUGHES MED INST,CHICAGO,IL 60637
来源：
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1989年 / 86卷 / 22期
关键词：
D O I：
10.1073/pnas.86.22.8977
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
引用
收藏
页码：8977 / 8981
页数：5
相关论文
共 34 条
[1]   MEASUREMENT OF CIRCULATING THYROID MICROSOMAL ANTIBODIES BY TANNED RED-CELL HEMAGGLUTINATION TECHNIQUE - ITS USEFULNESS IN DIAGNOSIS OF AUTOIMMUNE THYROID DISEASES [J].
AMINO, N ;
HAGEN, SR ;
YAMADA, N ;
REFETOFF, S .
CLINICAL ENDOCRINOLOGY, 1976, 5 (02) :115-125
[2]   POLYMORPHIC DNA REGION ADJACENT TO THE 5'-END OF THE HUMAN INSULIN GENE [J].
BELL, GI ;
KARAM, JH ;
RUTTER, WJ .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1981, 78 (09) :5759-5763
[3]   A NOVEL THYROID-HORMONE RECEPTOR ENCODED BY A CDNA CLONE FROM A HUMAN TESTIS LIBRARY [J].
BENBROOK, D ;
PFAHL, M .
SCIENCE, 1987, 238 (4828) :788-791
[4]   RESISTANCE TO THYROID-HORMONE DIAGNOSED BY THE REDUCED RESPONSE OF FIBROBLASTS TO THE TRIIODOTHYRONINE-INDUCED SUPPRESSION OF FIBRONECTIN SYNTHESIS [J].
CECCARELLI, P ;
REFETOFF, S ;
MURATA, Y .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1987, 65 (02) :242-246
[5]  
CHOMCZYNSKI P, 1987, ANAL BIOCHEM, V162, P156, DOI 10.1016/0003-2697(87)90021-2
[6]  
GLASS CK, 1987, NATURE, V329, P739
[7]   IDENTIFICATION OF A THYROID-HORMONE RECEPTOR THAT IS PITUITARY-SPECIFIC [J].
HODIN, RA ;
LAZAR, MA ;
WINTMAN, BI ;
DARLING, DS ;
KOENIG, RJ ;
LARSEN, PR ;
MOORE, DD ;
CHIN, WW .
SCIENCE, 1989, 244 (4900) :76-79
[8]   CHARACTERIZATION OF NUCLEAR THYROID-HORMONE RECEPTORS OF CULTURED SKIN FIBROBLASTS FROM PATIENTS WITH RESISTANCE TO THYROID-HORMONE [J].
ICHIKAWA, K ;
HUGHES, IA ;
HORWITZ, AL ;
DEGROOT, LJ .
METABOLISM-CLINICAL AND EXPERIMENTAL, 1987, 36 (04) :392-399
[9]   INHIBITION OF THYROID-HORMONE ACTION BY A NON-HORMONE BINDING C-ERBA PROTEIN GENERATED BY ALTERNATIVE MESSENGER-RNA SPLICING [J].
KOENIG, RJ ;
LAZAR, MA ;
HODIN, RA ;
BRENT, GA ;
LARSEN, PR ;
CHIN, WW ;
MOORE, DD .
NATURE, 1989, 337 (6208) :659-661
[10]   THYROID-HORMONE RECEPTOR BINDS TO A SITE IN THE RAT GROWTH-HORMONE PROMOTER REQUIRED FOR INDUCTION BY THYROID-HORMONE [J].
KOENIG, RJ ;
BRENT, GA ;
WARNE, RL ;
LARSEN, PR ;
MOORE, DD .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (16) :5670-5674
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