HALOGENATION USING N-HALOGEN COMPOUNDS .1. EFFECT OF AMINES ON ORTHO-BROMINATION OF PHENOLS WITH NBS

被引：66

作者：

FUJISAKI, S ^{[1
]}

EGUCHI, H ^{[1
]}

OMURA, A ^{[1
]}

OKAMOTO, A ^{[1
]}

NISHIDA, A ^{[1
]}

机构：

[1] TOSOH CO, CHEM RES LAB, YAMAGUCHI 746, JAPAN

来源：

BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN | 1993年 / 66卷 / 05期

关键词：

D O I：

10.1246/bcsj.66.1576

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Primary and secondary amines, especially diisopropylamine and dibutylamine, catalyzed ortho-dibromination of phenol and ortho-monobromination of 2-substituted phenols with NBS in dichloromethane to give selectively 2,6-dibromophenol and 2-bromo-6-substituted phenols, respectively. The effective intermediates are inferred to be N-bromoamines. The scope and limitations of the bromination are also presented.

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页码：1576 / 1579

页数：4

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